14
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Bone cysts: unicameral and aneurysmal bone cyst.

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Simple and aneurysmal bone cysts are benign lytic bone lesions, usually encountered in children and adolescents. Simple bone cyst is a cystic, fluid-filled lesion, which may be unicameral (UBC) or partially separated. UBC can involve all bones, but usually the long bone metaphysis and otherwise primarily the proximal humerus and proximal femur. The classic aneurysmal bone cyst (ABC) is an expansive and hemorrhagic tumor, usually showing characteristic translocation. About 30% of ABCs are secondary, without translocation; they occur in reaction to another, usually benign, bone lesion. ABCs are metaphyseal, excentric, bulging, fluid-filled and multicameral, and may develop in all bones of the skeleton. On MRI, the fluid level is evocative. It is mandatory to distinguish ABC from UBC, as prognosis and treatment are different. UBCs resolve spontaneously between adolescence and adulthood; the main concern is the risk of pathologic fracture. Treatment in non-threatening forms consists in intracystic injection of methylprednisolone. When there is a risk of fracture, especially of the femoral neck, surgery with curettage, filling with bone substitute or graft and osteosynthesis may be required. ABCs are potentially more aggressive, with a risk of bone destruction. Diagnosis must systematically be confirmed by biopsy, identifying soft-tissue parts, as telangiectatic sarcoma can mimic ABC. Intra-lesional sclerotherapy with alcohol is an effective treatment. In spinal ABC and in aggressive lesions with a risk of fracture, surgical treatment should be preferred, possibly after preoperative embolization. The risk of malignant transformation is very low, except in case of radiation therapy.

          Related collections

          Author and article information

          Journal
          Orthop Traumatol Surg Res
          Orthopaedics & traumatology, surgery & research : OTSR
          Elsevier BV
          1877-0568
          1877-0568
          Feb 2015
          : 101
          : 1 Suppl
          Affiliations
          [1 ] Clinique Arago, 93, boulevard Arago, 75014 Paris, France; Service de chirurgie orthopédique, hôpital Necker, 149, rue de Sèvres, 75015 Paris, France; Département de pédiatrie, institut Gustave-Roussy, 94805 Villejuif cedex, France. Electronic address: eric.mascard@wanadoo.fr.
          [2 ] Clinique Arago, 93, boulevard Arago, 75014 Paris, France; Service d'anatomopathologie, institut universitaire du cancer de Toulouse oncopole, Toulouse, France.
          [3 ] Clinique Arago, 93, boulevard Arago, 75014 Paris, France; Service de radiologie pédiatrique, hôpital Necker-Enfants-Malades, 149, rue de Sèvres, 75015 Paris, France.
          Article
          S1877-0568(14)00333-8
          10.1016/j.otsr.2014.06.031
          25579825
          7d555394-2a22-4abb-bf94-2270b2ca87f4
          History

          Bone tumor,Curettage,Biopsy,Aneurysmal bone cyst,Unicameral bone cyst,Simple bone cyst

          Comments

          Comment on this article