For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
41
views
109
references
 Top references
cited by
10
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      446
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Neuropsychology in Temporal Lobe Epilepsy: Influences from Cognitive Neuroscience and Functional Neuroimaging

      review-article
      Author(s): 1 , 2 , * , 1 , 2
      Publication date (Electronic):
      Journal: Epilepsy Research and Treatment
      Publisher: Hindawi Publishing Corporation

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Neuropsychologists assist in diagnosis (i.e., localization of dysfunction) and in prediction (i.e., how cognition may change following surgery) in individuals being considered for temporal lobe surgery. The current practice includes behavioural testing as well as mapping function via stimulation, inactivation, and (more recently) functional imaging. These methods have been providing valuable information in surgical planning for 60 years. Here, we discuss current assessment strategies and highlight how they are evolving, particularly with respect to integrating recent advances in cognitive neuroscience.

          Related collections

          Most cited references109

          • Record: found
          • Abstract: found
          • Article: not found

          The neurobiology of consolidations, or, how stable is the engram?

          Yadin Dudai (2004)
          Consolidation is the progressive postacquisition stabilization of long-term memory. The term is commonly used to refer to two types of processes: synaptic consolidation, which is accomplished within the first minutes to hours after learning and occurs in all memory systems studied so far; and system consolidation, which takes much longer, and in which memories that are initially dependent upon the hippocampus undergo reorganization and may become hippocampal-independent. The textbook account of consolidation is that for any item in memory, consolidation starts and ends just once. Recently, a heated debate has been revitalized on whether this is indeed the case, or, alternatively, whether memories become labile and must undergo some form of renewed consolidation every time they are activated. This debate focuses attention on fundamental issues concerning the nature of the memory trace, its maturation, persistence, retrievability, and modifiability.
          Article 0 comments Cited 350 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            The functional neuroanatomy of autobiographical memory: a meta-analysis.

            Eva Svoboda, Margaret McKinnon, Brian Levine (2006)
            Autobiographical memory (AM) entails a complex set of operations, including episodic memory, self-reflection, emotion, visual imagery, attention, executive functions, and semantic processes. The heterogeneous nature of AM poses significant challenges in capturing its behavioral and neuroanatomical correlates. Investigators have recently turned their attention to the functional neuroanatomy of AM. We used the effect-location method of meta-analysis to analyze data from 24 functional imaging studies of AM. The results indicated a core neural network of left-lateralized regions, including the medial and ventrolateral prefrontal, medial and lateral temporal and retrosplenial/posterior cingulate cortices, the temporoparietal junction and the cerebellum. Secondary and tertiary regions, less frequently reported in imaging studies of AM, are also identified. We examined the neural correlates of putative component processes in AM, including, executive functions, self-reflection, episodic remembering and visuospatial processing. We also separately analyzed the effect of select variables on the AM network across individual studies, including memory age, qualitative factors (personal significance, level of detail and vividness), semantic and emotional content, and the effect of reference conditions. We found that memory age effects on medial temporal lobe structures may be modulated by qualitative aspects of memory. Studies using rest as a control task masked process-specific components of the AM neural network. Our findings support a neural distinction between episodic and semantic memory in AM. Finally, emotional events produced a shift in lateralization of the AM network with activation observed in emotion-centered regions and deactivation (or lack of activation) observed in regions associated with cognitive processes.
            Article 0 comments Cited 342 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging.

              S Ogawa, D Tank, R. Menon … (1992)
              We report that visual stimulation produces an easily detectable (5-20%) transient increase in the intensity of water proton magnetic resonance signals in human primary visual cortex in gradient echo images at 4-T magnetic-field strength. The observed changes predominantly occur in areas containing gray matter and can be used to produce high-spatial-resolution functional brain maps in humans. Reducing the image-acquisition echo time from 40 msec to 8 msec reduces the amplitude of the fractional signal change, suggesting that it is produced by a change in apparent transverse relaxation time T*2. The amplitude, sign, and echo-time dependence of these intrinsic signal changes are consistent with the idea that neural activation increases regional cerebral blood flow and concomitantly increases venous-blood oxygenation.
              Article 0 comments Cited 235 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Journal ID (nlm-ta): Epilepsy Res Treat
                Journal ID (iso-abbrev): Epilepsy Res Treat
                Journal ID (publisher-id): ERT
                Title: Epilepsy Research and Treatment
                Publisher: Hindawi Publishing Corporation
                ISSN (Print): 2090-1348
                ISSN (Electronic): 2090-1356
                Publication date (Print): 2012
                Publication date (Electronic): 30 January 2012
                Volume: 2012
                Electronic Location Identifier: 925238
                Affiliations
                1Krembil Neuroscience Centre, University Health Network 4F-409, 399 Bathurst Street, Toronto, ON, Canada M5T 2S8
                2Department of Psychology, University of Toronto, Toronto, ON, Canada M5S 1A1
                Author notes

                Academic Editor: Seyed M. Mirsattari

                Article
                DOI: 10.1155/2012/925238
                PMC ID: 3420484
                PubMed ID: 22957249
                SO-VID: 7da153a6-f707-4046-9277-e5b3bca6a1c6
                Copyright © Copyright © 2012 M. P. McAndrews and M. Cohn.
                License:

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Date received : 4 July 2011
                Date accepted : 9 October 2011
                Categories
                Subject: Review Article

                ScienceOpen disciplines: Neurology
                Data availability:
                ScienceOpen disciplines: Neurology

                Comments

                Comment on this article

                scite_

                Similar content446

                See all similar

                Cited by10

                See all cited by

                Most referenced authors950

                See all reference authors