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      Burnout and risk of cardiovascular disease: Evidence, possible causal paths, and promising research directions.

      , , , ,
      Psychological Bulletin
      American Psychological Association (APA)

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          Abstract

          Burnout is characterized by emotional exhaustion, physical fatigue, and cognitive weariness, resulting from prolonged exposure to work-related stress. The authors review the accumulated evidence suggesting that burnout and the related concept of vital exhaustion are associated with increased risk of cardiovascular disease and cardiovascular-related events. The authors present evidence supporting several potential mechanisms linking burnout with ill health, including the metabolic syndrome, dysregulation of the hypothalamic-pituitary-adrenal axis along with sympathetic nervous system activation, sleep disturbances, systemic inflammation, impaired immunity functions, blood coagulation and fibrinolysis, and poor health behaviors. The association of burnout and vital exhaustion with these disease mediators suggests that their impact on health may be more extensive than currently indicated. Copyright 2006 APA, all rights reserved.

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              An Inventory for Measuring Depression

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                Author and article information

                Contributors
                Journal
                Psychological Bulletin
                Psychological Bulletin
                American Psychological Association (APA)
                1939-1455
                0033-2909
                2006
                2006
                : 132
                : 3
                : 327-353
                Article
                10.1037/0033-2909.132.3.327
                16719565
                7e18adb8-f11e-444c-af81-702f0ad804ea
                © 2006
                History

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