[Experimental fusion of the sheep cervical spine. Part II: Effect of growth factors and carrier systems on interbody fusion].

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Abstract

A sheep cervical spine interbody fusion model was used to determine the effect of different carriers and growth factors on interbody bone matrix formation. The purpose of this study was to compare the efficacy and safety of combined IGF-I and TGF-beta1 application with BMP-2 application in spinal fusion. Additionally, a new poly (D, L-lactide) carrier system was compared to a collagen sponge carrier.

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Journal

Journal ID (iso-abbrev): Chirurg

Title: Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen

Publisher: Springer Nature

ISSN: 0009-4722

ISSN (Print): 0009-4722

Publication date (Electronic): Oct 2002

Volume: 73

Issue: 10

Affiliations

[1 ] Unfall und Wiederherstellungschirurgie, Universitätsklinikum Charité der Humboldt-Universität Berlin, Campus Virchow-Klinikum, Germany. frank.kandziora@charite.de

Article

DOI: 10.1007/s00104-002-0490-9

PubMed ID: 12395162

SO-VID: 7ec4e0c6-425b-49fa-84da-a50d21013b18

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