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Variation in the definition of biochemical recurrence in patients treated for localized prostate cancer: the American Urological Association Prostate Guidelines for Localized Prostate Cancer Update Panel report and recommendations for a standard in the reporting of surgical outcomes.
Michael S Cookson
1 ,
Gunnar Aus ,
Arthur L Burnett ,
Edith D Canby-Hagino ,
Anthony V D'Amico ,
Roger R Dmochowski ,
David T Eton ,
Jeffrey D Forman ,
S Larry Goldenberg ,
Javier Hernandez ,
Celestia S Higano ,
Stephen R Kraus ,
Judd W Moul ,
Catherine Tangen ,
J Brantley Thrasher ,
Ian Thompson
Feb 2007
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Abstract
The American Urological Association Prostate Guideline Update Panel was charged with updating the Guidelines for Clinically Localized Prostate Cancer. In assessing outcomes with treatment, it became apparent that a highly variable number of definitions exist with respect to biochemical recurrence. Herein, we review the variability in published definitions of biochemical recurrence and make recommendations directed toward improving this terminology by recommending a standard definition in patients treated with radical prostatectomy.