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      Research on multi-modal autonomous diagnosis algorithm of COVID-19 based on whale optimized support vector machine and improved D-S evidence fusion

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          Abstract

          Aiming at the problem that the single CT image signal feature recognition method in the self-diagnosis of diseases cannot accurately and reliably classify COVID-19, and it is easily confused with suspected cases. The collected CT signals and experimental indexes are extracted to construct different feature vectors. The support vector machine is optimized by the improved whale algorithm for the preliminary diagnosis of COVID-19, and the basic probability distribution function of each evidence is calculated by the posterior probability modeling method. Then the similarity measure is introduced to optimize the basic probability distribution function. Finally, the multi-domain feature fusion prediction model is established by using the weighted D-S evidence theory. The experimental results show that the fusion of multi-domain feature information by whale optimized support vector machine and improved D-S evidence theory can effectively improve the accuracy and the precision of COVID-19 autonomous diagnosis. The method of replacing a single feature parameter with multi-modal indicators (CT, routine laboratory indexes, serum cytokines and chemokines) provides a more reliable signal source for the diagnosis model, which can effectively distinguish COVID-19 from the suspected cases.

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          Most cited references53

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          Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review

          The coronavirus disease 2019 (COVID-19) pandemic, due to the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused a worldwide sudden and substantial increase in hospitalizations for pneumonia with multiorgan disease. This review discusses current evidence regarding the pathophysiology, transmission, diagnosis, and management of COVID-19.
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            Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases

            Background Chest CT is used for diagnosis of 2019 novel coronavirus disease (COVID-19), as an important complement to the reverse-transcription polymerase chain reaction (RT-PCR) tests. Purpose To investigate the diagnostic value and consistency of chest CT as compared with comparison to RT-PCR assay in COVID-19. Methods From January 6 to February 6, 2020, 1014 patients in Wuhan, China who underwent both chest CT and RT-PCR tests were included. With RT-PCR as reference standard, the performance of chest CT in diagnosing COVID-19 was assessed. Besides, for patients with multiple RT-PCR assays, the dynamic conversion of RT-PCR results (negative to positive, positive to negative, respectively) was analyzed as compared with serial chest CT scans for those with time-interval of 4 days or more. Results Of 1014 patients, 59% (601/1014) had positive RT-PCR results, and 88% (888/1014) had positive chest CT scans. The sensitivity of chest CT in suggesting COVID-19 was 97% (95%CI, 95-98%, 580/601 patients) based on positive RT-PCR results. In patients with negative RT-PCR results, 75% (308/413) had positive chest CT findings; of 308, 48% were considered as highly likely cases, with 33% as probable cases. By analysis of serial RT-PCR assays and CT scans, the mean interval time between the initial negative to positive RT-PCR results was 5.1 ± 1.5 days; the initial positive to subsequent negative RT-PCR result was 6.9 ± 2.3 days). 60% to 93% of cases had initial positive CT consistent with COVID-19 prior (or parallel) to the initial positive RT-PCR results. 42% (24/57) cases showed improvement in follow-up chest CT scans before the RT-PCR results turning negative. Conclusion Chest CT has a high sensitivity for diagnosis of COVID-19. Chest CT may be considered as a primary tool for the current COVID-19 detection in epidemic areas. A translation of this abstract in Farsi is available in the supplement. - ترجمه چکیده این مقاله به فارسی، در ضمیمه موجود است.
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              World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19)

              An unprecedented outbreak of pneumonia of unknown aetiology in Wuhan City, Hubei province in China emerged in December 2019. A novel coronavirus was identified as the causative agent and was subsequently termed COVID-19 by the World Health Organization (WHO). Considered a relative of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), COVID-19 is caused by a betacoronavirus named SARS-CoV-2 that affects the lower respiratory tract and manifests as pneumonia in humans. Despite rigorous global containment and quarantine efforts, the incidence of COVID-19 continues to rise, with 90,870 laboratory-confirmed cases and over 3,000 deaths worldwide. In response to this global outbreak, we summarise the current state of knowledge surrounding COVID-19.
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                Author and article information

                Journal
                Comput Biol Med
                Comput Biol Med
                Computers in Biology and Medicine
                Elsevier Ltd.
                0010-4825
                1879-0534
                5 October 2022
                5 October 2022
                : 106181
                Affiliations
                [a ]State Key Laboratory of Intelligent Control and Decision of Complex Systems, School of Automation, Beijing Institute of Technology, Beijing 100081, China
                [b ]Department of Cardiology, The Second Medical Center, National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, China
                Author notes
                [* ]Corresponding author.
                Article
                S0010-4825(22)00889-7 106181
                10.1016/j.compbiomed.2022.106181
                9533636
                36240596
                7f18cd5b-baa1-4f0e-b048-da0c4bf5374b
                © 2022 Elsevier Ltd. All rights reserved.

                Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

                History
                : 28 July 2022
                : 19 September 2022
                : 1 October 2022
                Categories
                Article

                covid-19,multi-modal information,support vector machine,d-s evidence theory,whale optimization algorithm

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