Hormone Replacement Therapy Versus the Combined Oral Contraceptive Pill in Premature Ovarian Failure: A Randomized Controlled Trial of the Effects on Bone Mineral Density.

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Abstract

Women with premature ovarian failure (POF) face many years of estrogen deficiency. One of the major consequences is bone loss. The optimal form of estrogen replacement is unknown and management is not evidence based. The 2 broad options are combined hormone replacement therapy (HRT) or the combined oral contraceptive pill (COCP).

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Author and article information

Journal

Journal ID (iso-abbrev): J. Clin. Endocrinol. Metab.

Title: The Journal of clinical endocrinology and metabolism

Publisher: The Endocrine Society

ISSN (Electronic): 1945-7197

ISSN (Print): 0021-972X

Publication date (Electronic): Sep 2016

Volume: 101

Issue: 9

Affiliations

[1 ] Menopause Research Unit (B.C., J.Ro., J.Ry.), McNair Centre, and Department of Nuclear Medicine (I.F.), Guy's Hospital, London, SE1 9RT, United Kingdom; and Department of Women's Health (P.T.S.), St Thomas' Hospital, London SE1 7EH, United Kingdom.

Article

DOI: 10.1210/jc.2015-4063

PubMed ID: 27340881

SO-VID: 7f225d54-46c3-4abf-8bd7-8b0123f9c77a

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