Immunohistochemical Assessment of the Diagnostic Utility of PD-L1 (Clone SP142) for Methotrexate-Associated Lymphoproliferative Disorders With an Emphasis of Neoplastic PD-L1 (Clone SP142)-Positive Classic Hodgkin Lymphoma Type.

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Abstract

We describe results of programmed death ligand 1 (PD-L1) immunohistochemical assessment in methotrexate (MTX)-associated lymphoproliferative disorders (LPDs) and highlight the characteristics of classic Hodgkin lymphoma (CHL) type MTX-LPD.

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Journal

Journal ID (iso-abbrev): Am J Clin Pathol

Title: American journal of clinical pathology

Publisher: Oxford University Press (OUP)

ISSN (Electronic): 1943-7722

ISSN (Print): 0002-9173

Publication date (Electronic): April 15 2020

Volume: 153

Issue: 5

Affiliations

[1 ] Department of Pathology and Laboratory Medicine, Nagoya University Hospital, Nagoya, Japan.

[2 ] Department of Pathology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

[3 ] Department of Surgical Pathology, Aichi Medical University Hospital, Nagakute, Japan.

[4 ] Department of Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital, Nagoya, Japan.

[5 ] Department of Clinical Laboratory, Nagano Prefectural Shinshu Medical Center, Nagano, Japan.

Article

Publisher Item ID: 5707435

DOI: 10.1093/ajcp/aqz198

PubMed ID: 31977037

SO-VID: 7f310052-fcb8-45dd-ba2c-9611b580a9be

History

Keywords: lassic Hodgkin lymphoma,lone SP142,eoplastic PD-L1 expression,Methotrexate-associated lymphoproliferative disorder

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Keywords: lassic Hodgkin lymphoma, lone SP142, eoplastic PD-L1 expression, Methotrexate-associated lymphoproliferative disorder

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