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Prostate-specific membrane antigen PET-CT in patients with high-risk prostate cancer before curative-intent surgery or radiotherapy (proPSMA): a prospective, randomised, multi-centre study
Michael S Hofman ,
Nathan Lawrentschuk ,
Roslyn J Francis ,
Colin Tang ,
Ian Vela ,
Paul Thomas ,
Natalie Rutherford ,
Jarad M Martin ,
Mark Frydenberg ,
Ramdave Shakher ,
Lih-Ming Wong ,
Kim Taubman ,
Sze Ting Lee ,
Edward Hsiao ,
Paul Roach ,
Michelle Nottage ,
Ian Kirkwood ,
Dickon Hayne ,
Emma Link ,
Petra Marusic ,
Anetta Matera ,
Alan Herschtal ,
Amir Iravani ,
Rodney J Hicks ,
Scott Williams ,
Declan G Murphy
March 2020
March 2020
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Abstract
Conventional imaging using CT and bone scan has insufficient sensitivity when staging
men with high-risk localised prostate cancer. We aimed to investigate whether novel
imaging using prostate-specific membrane antigen (PSMA) PET-CT might improve accuracy
and affect management.