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      Review of Systemic Treatment Options for Adult Atopic Dermatitis.

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          Abstract

          Atopic dermatitis (AD) is a chronic, pruritic inflammatory skin disease resulting from defects in skin barrier and aberrant immune responses. AD significantly affects the quality of life. Not all patients respond to topical therapies, and often systemic therapy is required to control the disease.

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          Author and article information

          Journal
          J Cutan Med Surg
          Journal of cutaneous medicine and surgery
          SAGE Publications
          1615-7109
          1203-4754
          September 17 2016
          : 21
          : 1
          Affiliations
          [1 ] 1 Queen's University, SKiN Centre for Dermatology, and Probity Medical Research, Peterborough, ON, Canada.
          [2 ] 2 Lynde Dermatology, Probity Medical Research, Markham Ontario, and Department of Medicine, University of Toronto, Toronto, ON, Canada.
          [3 ] 3 K Papp Clinical Research and Probity Medical Research, Waterloo, ON, Canada.
          [4 ] 4 University of Sherbrooke, QC, Canada.
          [5 ] 5 University of Western Ontario, London ON, Canada.
          [6 ] 6 Memorial University of Newfoundland St. John's, NL, Canada.
          [7 ] 7 Department of Dermatology and Skin Science, University of British Columbia, and Probity Medical Research, Surrey, BC, Canada.
          [8 ] 8 Laval University and CDQM and CRDQ, Quebec, QC, Canada.
          [9 ] 9 Division of Clinical Immunology and Allergy, University of Toronto, Toronto, ON, Canada.
          [10 ] 10 Dermatrials Research Inc., Hamilton, ON, Canada.
          Article
          1203475416670364
          10.1177/1203475416670364
          27635033
          7fa3af1c-31c1-4381-9738-903be2d0913d
          History

          IL-13,IL-4,adults,atopic dermatitis,biologics,dupilumab,systemic therapy

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