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      Thyroid Incidentalomas

      Hormone Research in Paediatrics

      S. Karger AG

      Thyroid nodules, Thyroid ultrasound, Thyroid incidentalomas, Fine needle aspiration cytology

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          Abstract

          Background: The prevalence of thyroid nodules in the general population varies according to the method of detection in use. In large population studies, about 5% of subjects have palpable thyroid nodules, while autopsy studies reveal a 49–57% prevalence of thyroid nodules that were asymptomatic during life, and thyroid ultrasonography (US) shows a 13–50% prevalence in the general population. The increased sensitivity of many imaging modalities has led, in turn, to increased detection of subclinical thyroid nodules and of small, nonpalpable incidentalomas, and a diagnostic approach to patients with these nodules is briefly summarized. Conclusions: Despite the high prevalence of thyroid nodules discovered by US, clinically relevant thyroid malignancy remains rare and can be managed conservatively in most cases.

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          Most cited references 8

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          Management of a solitary thyroid nodule.

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            Thyroid incidentalomas. Prevalence by palpation and ultrasonography.

             S. Ezzat (1994)
            Thyroid nodules are commonly identified on autopsy examination. There are relatively few descriptions, however, of the frequency with which thyroid nodules are encountered incidentally during the course of other investigations. Prospective study to examine the prevalence of thyroid nodules in asymptomatic North American subjects, with palpation findings compared with findings on high-resolution ultrasonography. Palpable nodules were identified in 21 (21%) of 100 subjects, with nine solitary nodules (9%) and 12 multiple nodules (12%). In comparison, only 33 subjects were found to be free of any nodules by ultrasonography. Of the 67 subjects with abnormal ultrasound findings, 22 had solitary nodules (22%) and 45 had multiple nodules (45%). The prevalence of nodules was greater in women (72%) than in men (41%) (P < .02). A concordance rate of 49% was noted between ultrasound and findings by palpation. The data indicate that thyroid abnormalities are very common incidental findings, emphasizing the need for a conservative approach when such lesions are encountered incidentally.
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              Gross and microscopic findings in clinically normal thyroid glands.

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                Author and article information

                Journal
                HRE
                Horm Res Paediatr
                10.1159/issn.1663-2818
                Hormone Research in Paediatrics
                S. Karger AG
                978-3-8055-8475-3
                978-3-8055-8476-0
                1663-2818
                1663-2826
                2007
                December 2007
                10 December 2007
                : 68
                : Suppl 5
                : 199-201
                Affiliations
                Department of Endocrinology, University of Pisa, Pisa, Italy
                Article
                110625 Horm Res 2007;68:199–201
                10.1159/000110625
                18174746
                © 2007 S. Karger AG, Basel

                Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

                Page count
                References: 20, Pages: 3
                Categories
                Adult Clinical Session: Endocrine Incidentalomas

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