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      Thyroid Incidentalomas

      Hormone Research in Paediatrics

      S. Karger AG

      Thyroid nodules, Thyroid ultrasound, Thyroid incidentalomas, Fine needle aspiration cytology

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          Background: The prevalence of thyroid nodules in the general population varies according to the method of detection in use. In large population studies, about 5% of subjects have palpable thyroid nodules, while autopsy studies reveal a 49–57% prevalence of thyroid nodules that were asymptomatic during life, and thyroid ultrasonography (US) shows a 13–50% prevalence in the general population. The increased sensitivity of many imaging modalities has led, in turn, to increased detection of subclinical thyroid nodules and of small, nonpalpable incidentalomas, and a diagnostic approach to patients with these nodules is briefly summarized. Conclusions: Despite the high prevalence of thyroid nodules discovered by US, clinically relevant thyroid malignancy remains rare and can be managed conservatively in most cases.

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          Most cited references 8

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          Management of a solitary thyroid nodule.

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            Thyroid incidentalomas. Prevalence by palpation and ultrasonography.

             S. Ezzat (1994)
            Thyroid nodules are commonly identified on autopsy examination. There are relatively few descriptions, however, of the frequency with which thyroid nodules are encountered incidentally during the course of other investigations. Prospective study to examine the prevalence of thyroid nodules in asymptomatic North American subjects, with palpation findings compared with findings on high-resolution ultrasonography. Palpable nodules were identified in 21 (21%) of 100 subjects, with nine solitary nodules (9%) and 12 multiple nodules (12%). In comparison, only 33 subjects were found to be free of any nodules by ultrasonography. Of the 67 subjects with abnormal ultrasound findings, 22 had solitary nodules (22%) and 45 had multiple nodules (45%). The prevalence of nodules was greater in women (72%) than in men (41%) (P < .02). A concordance rate of 49% was noted between ultrasound and findings by palpation. The data indicate that thyroid abnormalities are very common incidental findings, emphasizing the need for a conservative approach when such lesions are encountered incidentally.
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              Gross and microscopic findings in clinically normal thyroid glands.


                Author and article information

                Horm Res Paediatr
                Hormone Research in Paediatrics
                S. Karger AG
                December 2007
                10 December 2007
                : 68
                : Suppl 5
                : 199-201
                Department of Endocrinology, University of Pisa, Pisa, Italy
                110625 Horm Res 2007;68:199–201
                © 2007 S. Karger AG, Basel

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                Page count
                References: 20, Pages: 3
                Adult Clinical Session: Endocrine Incidentalomas


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