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Reduced syndecan-1 expression is correlated with the histological grade of malignancy at the deep invasive front in oral squamous cell carcinoma.
Hideo Kurokawa
1 ,
Min Zhang ,
Shinobu Matsumoto ,
Yoshihiro Yamashita ,
Toshiko Tanaka ,
Koichi Takamori ,
Kaori Igawa ,
Maho Yoshida ,
Hiroshi Fukuyama ,
Tetsu Takahashi ,
Sumio Sakoda
May 2006
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Abstract
Although many histopathological characteristics of oral squamous cell carcinoma (O-SCC) have been identified as prognostic factors, no factor is completely accurate and unequivocal. This study evaluated the association between the loss of syndecan-1 expression and the histological grade of malignancy at the deep invasive front in O-SCC.