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      Spontaneous thrombosis in giant intracranial aneurysms.

      Journal of Neurology, Neurosurgery, and Psychiatry
      Cerebral Infarction, diagnosis, Humans, Intracranial Aneurysm, Intracranial Embolism and Thrombosis, Subarachnoid Hemorrhage, Tomography, X-Ray Computed

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          Abstract

          Twelve patients in a series of 22 with giant intracranial aneurysms demonstrated neuroradiological features of partial or total spontaneous intra-aneurysmal thrombosis. The presence of this intra-aneurysmal clot significantly altered the computed tomographic appearance of the giant aneurysm. Massive intra-aneurysmal thrombosis did not protect against subarachnoid haemorrhage and the likelihood of rupture of a clot containing giant aneurysm was not significantly different from that of a non-thrombosed giant aneurysm. Although parent artery occlusion from a thrombosed giant aneurysm, and massive aneurysmal thrombosis leading to the formation of giant serpentine aneurysm were documented, these are rare epiphenomena. The risk of embolisation from a partially thrombosed giant aneurysm, which was documented in one case, would appear to be greater than that from a non-thrombosed giant aneurysm. The findings in this series, and a review of literature, suggest that the presence of intra-aneurysmal clot in giant intracranial aneurysms has little prognostic significance and does not alter the management or outcome after treatment.

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          Author and article information

          Journal
          7175528
          491643
          10.1136/jnnp.45.11.1040

          Chemistry
          Cerebral Infarction,diagnosis,Humans,Intracranial Aneurysm,Intracranial Embolism and Thrombosis,Subarachnoid Hemorrhage,Tomography, X-Ray Computed

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