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      Experimental analysis of clinical applicability of homemade in homogeneous phantom

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          Abstract

          Objective To conduct experimental analysis of clinical applicability of a homemade phantom which is equivalent to multiple tissue densities of human body.

          Methods Materials with densities close to bone, lung, cavity, and soft tissue were manufactured and combined to obtain a homemade in homogeneous phantom. The electron density of equivalent materials was compared with the organs. Ten lung cancer patients in our department were recruited for dose verification of intensity modulated radiation therapy in the homemade phantom and solid-water phantom. The two phantoms were compared for characteristics in dose verification, and the dosimetric differences of the homemade phantom between the calculated values on treatment planning systemand measured values were statistically analyzed by SPSS 21.0 software.

          Results In the dose verification, the gamma pass rates (3 mm/3%) were more than 90% using both the homemade phantom and solid-water phantom. The measured values in homemade phantom were larger than those in solid-water phantom, and the maximum deviation was 11.5%. The AD and RD values of gamma pass rate in dose verification showed no significant differences between the two phantoms ( P > 0.05).

          Conclusion The homemade phantom meets the accuracy requirement of clinical application and can be used in dose verification of intensity modulated radiation therapy plan.

          Abstract

          摘要: 目的 对自制等效于人体多种组织密度模体, 进行临床质控可应用性实验分析。 方法 自制密度接近骨骼、肺、空腔及软组织的模体材料, 并组合制作非均匀验证模体, 然后对器官等效材料的电子密度进行比较。选用本科收 治的 10 例肺癌患者, 分别在该自制模体和固体水模体上进行调强计划剂量验证, 比较 2 种模体在剂量验证领域的特 点, 并分析自制模体在 TPS 上的计算值与实测值的剂量学差异, 采用 SPSS 21.0 软件进行统计分析。 结果 使用自制 模体和固体水模体进行剂量验证, γ 通过率 (3 mm/3%) 均在 90% 以上。应用自制模体进行剂量验证的测量值, 比使用 固体水模体时偏大, 测量值最大偏差为 11.5%。2 种模体间的剂量验证 γ 通过率 AD 组和 RD 组差异无统计学意义 ( P > 0.05)。 结论 自制模体符合临床应用的精度要求, 可应用在放射治疗计划验证。

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          Author and article information

          Journal
          CJRH
          Chinese Journal of Radiological Health
          Chinese Preventive Medical Association (Ji’an, China )
          1004-714X
          01 October 2022
          01 December 2022
          : 31
          : 5
          : 606-610
          Affiliations
          [1] 1Department of Radiotherapy, Pizhou People’s Hospital, Xuzhou 221300 China
          [2] 2Department of Radiotherapy, Xuzhou Cancer Hospital, Xuzhou 221005 China
          Article
          j.issn.1004-714X.2022.05.016
          10.13491/j.issn.1004-714X.2022.05.016
          8044b9ab-5a08-4aa1-b1ae-877d48da2358
          © 2022 Chinese Journal of Radiological Health

          This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License (CC BY-NC 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc/4.0/.

          History
          Categories
          Journal Article

          Medicine,Image processing,Radiology & Imaging,Bioinformatics & Computational biology,Health & Social care,Public health
          CT value,Dose verification,Radiation therapy,Phantom,Tissue equivalent

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