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The Chemistry and Biology of Alkannin, Shikonin, and Related Naphthazarin Natural Products
Vassilios P. Papageorgiou ,
Andreana N. Assimopoulou ,
Elias A. Couladouros ,
David Hepworth ,
K. C. Nicolaou
February 01 1999
February 01 1999
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Abstract
<p class="first" id="d3480306e104">Wound healing properties of plant extracts that
contain the naphthoquinone natural
products alkannin (1) and shikonin (2) have been known for many centuries. More recently,
the biological properties of 1, 2, and related derivatives have been demonstrated
experimentally, and their production both by cell cultures and chemical synthesis
has been studied extensively.
</p>