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      The interdependence of behavioral and somatic health: implications for conceptualizing health and measuring treatment outcomes

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          Abstract

          Purpose

          The interdependence of behavioral and somatic aspects of various health conditions warrants greater emphasis on an integrated care approach.

          Theory

          We propose that integrated approaches to health and wellness require comprehensive and empirically-valid outcome measures to assess quality of care.

          Method

          We discuss the transition from independent to integrated treatment approaches and provide examples of new systems for integrated assessment of treatment outcome.

          Results

          Evidence suggests that support for an independent treatment approach is waning and momentum is building towards more integrated care. In addition, research evidence suggests integrated care improves health outcomes, and both physicians and patients have favorable impressions of integrated care.

          Conclusions

          As treatment goals in the integrated perspective expand to take into account the intimate relationships among mental illness, overall health, and quality of life, clinicians need to develop outcome measures that are similarly comprehensive.

          Discussion

          Increased recognition, by researchers, providers, and insurers, of the interdependence between behavioral and physical health holds great promise for innovative treatments that could significantly improve patients' lives.

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          Most cited references72

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          The prevalence of comorbid depression in adults with diabetes: a meta-analysis.

          To estimate the odds and prevalence of clinically relevant depression in adults with type 1 or type 2 diabetes. Depression is associated with hyperglycemia and an increased risk for diabetic complications; relief of depression is associated with improved glycemic control. A more accurate estimate of depression prevalence than what is currently available is needed to gauge the potential impact of depression management in diabetes. MEDLINE and PsycINFO databases and published references were used to identify studies that reported the prevalence of depression in diabetes. Prevalence was calculated as an aggregate mean weighted by the combined number of subjects in the included studies. We used chi(2) statistics and odds ratios (ORs) to assess the rate and likelihood of depression as a function of type of diabetes, sex, subject source, depression assessment method, and study design. A total of 42 eligible studies were identified; 20 (48%) included a nondiabetic comparison group. In the controlled studies, the odds of depression in the diabetic group were twice that of the nondiabetic comparison group (OR = 2.0, 95% CI 1.8-2.2) and did not differ by sex, type of diabetes, subject source, or assessment method. The prevalence of comorbid depression was significantly higher in diabetic women (28%) than in diabetic men (18%), in uncontrolled (30%) than in controlled studies (21%), in clinical (32%) than in community (20%) samples, and when assessed by self-report questionnaires (31%) than by standardized diagnostic interviews (11%). The presence of diabetes doubles the odds of comorbid depression. Prevalence estimates are affected by several clinical and methodological variables that do not affect the stability of the ORs.
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            Depression and poor glycemic control: a meta-analytic review of the literature.

            Depression is common among patients with diabetes, but its relationship to glycemic control has not been systematically reviewed. Our objective was to determine whether depression is associated with poor glycemic control. Medline and PsycINFO databases and published reference lists were used to identify studies that measured the association of depression with glycemic control. Meta-analytic procedures were used to convert the findings to a common metric, calculate effect sizes (ESs), and statistically analyze the collective data. A total of 24 studies satisfied the inclusion and exclusion criteria for the meta-analysis. Depression was significantly associated with hyperglycemia (Z = 5.4, P < 0.0001). The standardized ES was in the small-to-moderate range (0.17) and was consistent, as the 95% CI was narrow (0.13-0.21). The ES was similar in studies of either type 1 or type 2 diabetes (ES 0.19 vs. 0.16) and larger when standardized interviews and diagnostic criteria rather than self-report questionnaires were used to assess depression (ES 0.28 vs. 0.15). Depression is associated with hyperglycemia in patients with type 1 or type 2 diabetes. Additional studies are needed to establish the directional nature of this relationship and to determine the effects of depression treatment on glycemic control and the long-term course of diabetes.
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              Toward a syndrome model of addiction: multiple expressions, common etiology.

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                Author and article information

                Contributors
                Role: EdD,
                Harvard Medical School, Division on Addictions, 101 Station Landing, 2nd floor, Medford, MA 02155, USA
                Role: PhD,
                Harvard Medical School, Division on Addictions, 101 Station Landing, 2nd floor, Medford, MA 02155, USA
                Role: MPH,
                Cambridge Health Alliance, Division on Addictions, 101 Station Landing, Second Floor, Medford, MA 02155, USA
                Role: PhD, MBA,
                Corporate Clinical Department, ValueOptions, 240 Corporate Blvd, Norfolk, VA 23502, USA
                Role: PhD,
                Research and Outcomes Department, ValueOptions, 7286 Southampton Lane, West Chester, OH 45069, USA
                Role: MD,
                Medical Affairs Department, Massachusetts Behavioral Health Partnership, ValueOptions, 150 Federal Street, Boston, MA 02110, USA
                Role: PhD,
                Research and Outcomes Department, ValueOptions, Inc., 520 Pleasant Valley Road, Trafford, PA 1508, USA
                Role: PhD,
                Harvard Graduate School of Education, 8 Story Street, 5th Floor, Cambridge, MA 02138, USA
                Role: PhD, CAS,
                Harvard Medical School, Division on Addictions, 101 Station Landing, 2nd floor, Medford, MA 02155, USA
                Journal
                Int J Integr Care
                IJIC
                International Journal of Integrated Care
                Igitur, Utrecht Publishing & Archiving (Utrecht, The Netherlands )
                1568-4156
                Apr-Jun 2007
                16 May 2007
                : 7
                : e10
                Affiliations
                Harvard Medical School, Division on Addictions, 101 Station Landing, 2nd floor, Medford, MA 02155, USA
                Harvard Medical School, Division on Addictions, 101 Station Landing, 2nd floor, Medford, MA 02155, USA
                Cambridge Health Alliance, Division on Addictions, 101 Station Landing, Second Floor, Medford, MA 02155, USA
                Corporate Clinical Department, ValueOptions, 240 Corporate Blvd, Norfolk, VA 23502, USA
                Research and Outcomes Department, ValueOptions, 7286 Southampton Lane, West Chester, OH 45069, USA
                Medical Affairs Department, Massachusetts Behavioral Health Partnership, ValueOptions, 150 Federal Street, Boston, MA 02110, USA
                Research and Outcomes Department, ValueOptions, Inc., 520 Pleasant Valley Road, Trafford, PA 1508, USA
                Harvard Graduate School of Education, 8 Story Street, 5th Floor, Cambridge, MA 02138, USA
                Harvard Medical School, Division on Addictions, 101 Station Landing, 2nd floor, Medford, MA 02155, USA
                Author notes
                Correspondence to: Richard A. LaBrie, EdD, Associate Director of Research and Data Analysis, Division on Addictions, Harvard Medical School, 101 Station Landing, 2nd floor, Medford, MA 02155, Phone: +781-306-8607, Fax: +781-306-8629. E-mail: rlabrie@ 123456hms.harvard.edu
                Article
                ijic200710
                1894673
                17627294
                808f56c7-712b-4bfb-b614-1329041828b1
                Copyright 2007, International Journal of Integrated Care (IJIC)
                History
                Categories
                Research and Theory
                Special issue: Infrastructures to support integrated care: connecting across institutional and professional boundaries

                Health & Social care
                quality of care,mental health,integrated care
                Health & Social care
                quality of care, mental health, integrated care

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