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      Desmopressin associated symptomatic hyponatremic hypervolemia in children. Are there predictive factors?

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          Abstract

          Desmopressin is widely used in primary nocturnal enuresis, bleeding disorders, central diabetes insipidus and diagnostic urine concentration testing. Hyponatremic hypervolemia leading to seizures has been reported as a rare but potentially life threatening side effect of desmopressin therapy. We sought to identify factors that predispose patients to hyponatremia and to find predictive factors associated with increased risk of water intoxication.

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          Author and article information

          Journal
          J. Urol.
          The Journal of urology
          0022-5347
          0022-5347
          Jul 2005
          : 174
          : 1
          Affiliations
          [1 ] Departments of Pediatric Nephrology, Charité Children's Hospital, Berlin, Germany.
          Article
          S0022-5347(05)60110-3
          10.1097/01.ju.0000161213.54024.7f
          15947670
          80a4b4ad-5b3f-44a8-9c68-8dd33d1e1df7
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