Relationship between the Level of c- myc  mRNA and Histologic Aggressiveness in Thyroid Tumors

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Abstract

We investigated the relationship between the level of c -myc mRNA and histologic aggressiveness in thyroid tumors obtained at surgery. In thyroid carcinomas, there was a positive correlation between these two parameters, while in benign tumors there was no correlation between cellularity and the expression of the proto-oncogene c -myc. These results might be useful in the prognosis of thyroid tumors and consequently helpful in the management of the patient.

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Journal

Journal ID (publisher-id): HRE

Journal ID (nlm-ta): Horm Res Paediatr

Journal ID (doi): 10.1159/issn.1663-2818

Title: Hormone Research in Paediatrics

Publisher: S. Karger AG

ISSN (Print): 1663-2818

ISSN (Electronic): 1663-2826

Publication date Subscription-year: 1993

Publication date (Print): 1993

Publication date (Electronic): 03 December 2008

Volume: 39

Issue: 3-4

Pages: 161-165

Affiliations

^aDepartment of Endocrinology, Fundación CIMAE; Departments of ^bEndocrinology and ^cPathology, Hospital Israelita ‘Ezrah’, Buenos Aires, Argentina

Article

Publisher ID: 182718 Other ID: Horm Res 1993;39:161–165

DOI: 10.1159/000182718

PubMed ID: 8262479

SO-VID: 80a75174-f9ee-4f0f-8f6d-43802a2aa94f

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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

History

Date received : 24 November 1992

Date accepted : 16 April 1993

Page count

Pages: 5

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Relationship between the Level of c- myc mRNA and Histologic Aggressiveness in Thyroid Tumors

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