Hypercholesterolemia Up-Regulates the Expression of Intermedin and Its Receptor Components in the Aorta of Rats via Inducing the Oxidative Stress.

Meng, Qingtao; Shi, Di; Feng, Jiayue; Su, Yanling; Long, Yang; He, Sen; Wang, Si Long; Wang, Yong; Zhang, Xiangxun; Chen, Xiaoping

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Hypercholesterolemia Up-Regulates the Expression of Intermedin and Its Receptor Components in the Aorta of Rats via Inducing the Oxidative Stress.

Author(s): Qingtao Meng ¹ , Di Shi ¹ , Jiayue Feng ¹ , Yanling Su ² , Yang Long ³ , Sen He ¹ , Si Wang ¹ , Yong Wang ¹ , Xiangxun Zhang ³ , Xiaoping Chen ⁴

Publication date (Electronic): 2016

Journal: Annals of clinical and laboratory science

Keywords: Hypercholesterolemia, Intermedin, Oxidative stress

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Abstract

Hypercholesterolemia can cause damage to the artery. Intermedin (IMD) is a novel member of the calcitonin gene-related peptide family. This study aims to investigate the aortic expression of IMD and its receptors in hypercholesterolemia without atherosclerosis.

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Journal ID (iso-abbrev): Ann. Clin. Lab. Sci.

Title: Annals of clinical and laboratory science

ISSN (Electronic): 1550-8080

ISSN (Print): 0091-7370

Publication date (Electronic): 2016

Volume: 46

Issue: 1

Affiliations

[1 ] Department of Cardiology, West China Hospital, Sichuan University, Chengdu, China.

[2 ] Department of Cardiology, Changhai Hospital, the Second Military Medical University, Shanghai, China.

[3 ] Laboratory of Endocrine and Metabolic Diseases, West China Hospital, Sichuan University, Chengdu, China.

[4 ] Department of Cardiology, West China Hospital, Sichuan University, Chengdu, China chenxp13@aliyun.com.

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Publisher Item ID: 46/1/5

PubMed ID: 26927337

SO-VID: 8110653a-1312-41e3-9ea8-6f5ce883efa3

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Keywords: Hypercholesterolemia,Intermedin,Oxidative stress

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Keywords: Hypercholesterolemia, Intermedin, Oxidative stress

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Hypercholesterolemia Up-Regulates the Expression of Intermedin and Its Receptor Components in the Aorta of Rats via Inducing the Oxidative Stress.

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