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      Patients’ Perceptions and ICU Clinicians Predictions of Quality of Life Following Critical Illness

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          Abstract

          Purpose

          To determine how patients perceive their quality of life (QOL) six months following critical illness and to measure clinicians’ discriminative accuracy of predicting this outcome.

          Materials and Methods

          This prospective cohort study of intensive care unit (ICU) survivors asked patients to report their QOL strictly at six months compared to one month before their critical illness as better, the same, or worse. ICU physicians and nurses made six-month QOL predictions for these patients..

          Results

          Of 162 critical illness survivors, 33% (n=53) of patients reported six-month QOL as better, 33% (n=54) the same, and 34% (n=55) worse. Abnormal cognition and inability to return to primary pastime or original place of residence (p<0.05 for all) were associated with worse self-reported QOL at six months in multivariable regression. Predictions of patient perceptions of QOL at six months were pessimistic and had low discriminative accuracy for both physicians (sensitivity 56%, specificity 53%) and nurses (sensitivity 49%, specificity 57%).

          Conclusions

          Among survivors of critical illness, one-third each reported their six-month post-ICU QOL as better, the same, or worse. Self-reported six-month QOL was associated with six-month function. ICU clinicians should use caution in predicting self-reported QOL, as discriminative accuracy was poor in this cohort.

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          Author and article information

          Journal
          8610642
          2512
          J Crit Care
          J Crit Care
          Journal of critical care
          0883-9441
          1557-8615
          11 March 2019
          01 October 2018
          December 2018
          01 December 2019
          : 48
          : 352-356
          Affiliations
          [1 ]Palliative and Advanced Illness Research (PAIR) Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
          [2 ]Sinai Health System, Toronto, Ontario
          [3 ]Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario
          [4 ]Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
          [5 ]Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania
          [6 ]Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
          [7 ]Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
          [8 ]Outcomes After Critical Illness and Surgery (OACIS) Group, Johns Hopkins University, Baltimore, Maryland
          [9 ]Division of Pulmonary and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland
          [10 ]Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland
          Author notes
          Corresponding author: Michael Detsky, Mount Sinai Hospital, 600 University Ave, 18-232-1, Toronto, Ontario, Canada, M5G 1X5, Phone: 416-586-4800 x5133, michael.detsky@ 123456sinaihealthsystem.ca

          Author contributions: Dr. Detsky had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Detsky, Mikkelsen, and Harhay; acquisition, analysis or interpretation of the data: Detsky, Delman, Buehler, Kent, and Ciuffetelli; drafting of the manuscript: Detsky, Kohn, Turnbull, and Harhay; critical revision of the manuscript for important intellectual content: all authors; statistical analysis: Detsky and Harhay; study supervision: Harhay.

          Article
          PMC6417499 PMC6417499 6417499 nihpa1012017
          10.1016/j.jcrc.2018.09.034
          6417499
          30296749
          8114adf7-f603-431b-afe0-292a1cbb180a
          History
          Categories
          Article

          functional status,critical illness,long-term outcomes,quality of life,survival

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