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      Desulfovibrio bacterial species are increased in ulcerative colitis.

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          Abstract

          Debate persists regarding the role of Desulfovibrio subspecies in ulcerative colitis. Combined microscopic and molecular techniques enable this issue to be investigated by allowing precise enumeration of specific bacterial species within the colonic mucous gel. The aim of this study was to combine laser capture microdissection and quantitative polymerase chain reaction to determine Desulfovibrio copy number in crypt-associated mucous gel in health and in acute and chronic ulcerative colitis.

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          Author and article information

          Journal
          Dis Colon Rectum
          Diseases of the colon and rectum
          Springer Science and Business Media LLC
          1530-0358
          0012-3706
          Nov 2010
          : 53
          : 11
          Affiliations
          [1 ] Department of Surgery, St. Vincent's University Hospital, UCD School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland.
          Article
          00003453-201011000-00011
          10.1007/DCR.0b013e3181f1e620
          20940602
          815bc9e2-fba6-429e-a938-5eb84b1ab02e
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