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      Brief structured respiration practices enhance mood and reduce physiological arousal

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          Summary

          Controlled breathwork practices have emerged as potential tools for stress management and well-being. Here, we report a remote, randomized, controlled study (NCT05304000) of three different daily 5-min breathwork exercises compared with an equivalent period of mindfulness meditation over 1 month. The breathing conditions are (1) cyclic sighing, which emphasizes prolonged exhalations; (2) box breathing, which is equal duration of inhalations, breath retentions, and exhalations; and (3) cyclic hyperventilation with retention, with longer inhalations and shorter exhalations. The primary endpoints are improvement in mood and anxiety as well as reduced physiological arousal (respiratory rate, heart rate, and heart rate variability). Using a mixed-effects model, we show that breathwork, especially the exhale-focused cyclic sighing, produces greater improvement in mood (p < 0.05) and reduction in respiratory rate (p < 0.05) compared with mindfulness meditation. Daily 5-min cyclic sighing has promise as an effective stress management exercise.

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          Highlights

          • Daily 5-minute breathwork and mindfulness meditation improve mood and reduce anxiety

          • Breathwork improves mood and physiological arousal more than mindfulness meditation

          • Cyclic sighing is most effective at improving mood and reducing respiratory rate

          Abstract

          In a remotely conducted randomized controlled trial, Yilmaz Balban et al. study the psychophysiological effects of controlled breathwork compared with mindfulness meditation. Breathwork produces greater improvement in mood and reduction in respiratory rate, while both result in reduction in negative emotion including state anxiety.

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          Most cited references66

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          Development and validation of brief measures of positive and negative affect: The PANAS scales.

          In recent studies of the structure of affect, positive and negative affect have consistently emerged as two dominant and relatively independent dimensions. A number of mood scales have been created to measure these factors; however, many existing measures are inadequate, showing low reliability or poor convergent or discriminant validity. To fill the need for reliable and valid Positive Affect and Negative Affect scales that are also brief and easy to administer, we developed two 10-item mood scales that comprise the Positive and Negative Affect Schedule (PANAS). The scales are shown to be highly internally consistent, largely uncorrelated, and stable at appropriate levels over a 2-month time period. Normative data and factorial and external evidence of convergent and discriminant validity for the scales are also presented.
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            • Article: not found

            Mindfulness-Based Interventions in Context: Past, Present, and Future

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              • Article: not found

              The positive and negative affect schedule (PANAS): construct validity, measurement properties and normative data in a large non-clinical sample.

              To evaluate the reliability and validity of the PANAS (Watson, Clark, & Tellegen, 1988b) and provide normative data. Cross-sectional and correlational. The PANAS was administered to a non-clinical sample, broadly representative of the general adult UK population (N = 1,003). Competing models of the latent structure of the PANAS were evaluated using confirmatory factor analysis. Regression and correlational analysis were used to determine the influence of demographic variables on PANAS scores as well as the relationship between the PANAS with measures of depression and anxiety (the HADS and the DASS). The best-fitting model (robust comparative fit index = .94) of the latent structure of the PANAS consisted of two correlated factors corresponding to the PA and NA scales, and permitted correlated error between items drawn from the same mood subcategories (Zevon & Tellegen, 1982). Demographic variables had only very modest influences on PANAS scores and the PANAS exhibited measurement invariance across demographic subgroups. The reliability of the PANAS was high, and the pattern of relationships between the PANAS and the DASS and HADS were consistent with tripartite theory. The PANAS is a reliable and valid measure of the constructs it was intended to assess, although the hypothesis of complete independence between PA and NA must be rejected. The utility of this measure is enhanced by the provision of large-scale normative data. Copyright 2004 The British Psychological Society

                Author and article information

                Contributors
                Journal
                Cell Rep Med
                Cell Rep Med
                Cell Reports Medicine
                Elsevier
                2666-3791
                10 January 2023
                17 January 2023
                10 January 2023
                : 4
                : 1
                : 100895
                Affiliations
                [1 ]Department of Neurobiology, School of Medicine, Stanford University, Stanford, CA 94305, USA
                [2 ]Department of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA 94305, USA
                [3 ]Stanford Center for Integrative Medicine, Stanford Health Care, Palo Alto, CA 94304, USA
                [4 ]Department of Bioengineering, School of Engineering and School of Medicine, Stanford University, Stanford, CA 94305, USA
                [5 ]Mental Illness Research Education and Clinical Center, VA Palo Alto Health Care Service, Palo Alto, CA 94304, USA
                [6 ]Center for Stress and Health, School of Medicine, Stanford University, Stanford, CA 94305, USA
                [7 ]Department of Ophthalmology, School of Medicine, Stanford University, Stanford, CA 94305, USA
                [8 ]BioX, School of Medicine, Stanford University, Stanford, CA 94305, USA
                Author notes
                []Corresponding author dspiegel@ 123456stanford.edu
                [∗∗ ]Corresponding author adh1@ 123456stanford.edu
                [9]

                Lead contact

                Article
                S2666-3791(22)00474-8 100895
                10.1016/j.xcrm.2022.100895
                9873947
                36630953
                815caf8b-fd85-459d-bf5b-a00dff84f7b6
                © 2022 The Authors

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

                History
                : 2 April 2022
                : 6 September 2022
                : 15 December 2022
                Categories
                Report

                breathwork,mindfulness meditation,mood,anxiety,wearable,physiology,heart rate variability,limbic,autonomic,stress,sleep

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