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      Should the tip-apex distance (TAD) rule be modified for the proximal femoral nail antirotation (PFNA)? A retrospective study

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          Abstract

          Background

          Unstable proximal femoral fractures are common and challenging for the orthopaedic surgeon. Often, these are treated with intramedullary nails. The most common mode of failure of any device to treat these fractures is cut-out. The Synthes proximal femoral nail antirotation (PFNA) is unique because it is the only proximal femoral intramedullary nail which employs a helical blade in lieu of a lag screw. The optimal tip-apex distance is 25 mm or less for a dynamic hip screw. The optimal blade tip placement is not known for the PFNA.

          Aim

          The aim of this study is to determine if the traditional tip-apex distance rule (<25 mm) applies to the PFNA.

          Method

          A retrospective study of all proximal femoral fractures treated with the PFNA in Western Australian public teaching hospitals between August 2006 and October 2007 was performed. Cases were identified from company and theatre implant use records. Patient demographic data was obtained from hospital records. Fractures were classified according to Arbeitsgemeinschaft für Osteosynthesefragen/Association for the Study of Internal Fixation. Fracture reduction, distal locking type and blade position within the head (tip-apex distance and Cleveland zone) were recorded from the intraoperative and immediate postoperative radiographs. Postoperative radiographs obtained in the routine treatment of patients were studied for review looking primarily for cut-out. Clinical outcomes were measured with the Oxford hip score.

          Results

          One hundred eighty-eight PFNAs were implanted during the study period, with 178 cases included in this study. Ninety-seven patients could be followed up clinically. There were 18 surgical implant-related failures (19%). The single most common mode of failure was cut-out in six cases (6.2%). Three cut-outs (two medial perforation and one varus collapse) occurred with tip-apex distance (TAD) less than 20 mm. There was no cut-out in cases where the TAD was from 20–30 mm. There were three implant-related failures (nail fracture, missed nail and loose locking screw), four implant-related femoral fractures, two non-unions, two delayed unions and one loss of reduction.

          Conclusion

          The PFNA is a suitable fixation device for the treatment of unstable proximal femoral fractures. There were still a relatively large number of cut-outs, and the tip-apex distance in the failures showed a bimodal distribution, not like previously demonstrated with dynamic hip screw. We propose that the helical blade behaves differently to a screw, and placement too close to the subchondral bone may lead to penetration through the head.

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          Most cited references21

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          The value of the tip-apex distance in predicting failure of fixation of peritrochanteric fractures of the hip.

          Failure of fixation of peritrochanteric fractures that have been treated with a fixed-angle sliding hip-screw device is frequently related to the position of the lag screw in the femoral head. A simple measurement has been developed to describe the position of the screw. This measurement, the tip-apex distance, is the sum of the distance from the tip of the lag screw to the apex of the femoral head on an anteroposterior radiograph and this distance on a lateral radiograph, after controlling for magnification. To determine the value of this measurement in the prediction of so-called cutout of the lag screw, 198 peritrochanteric fractures (193 patients) were studied. The minimum duration of follow-up was three months (average, thirteen months), during which period all of the fractures either healed or had failure of the fixation. Of the nineteen failures that were identified, sixteen were due to the device cutting out of the femoral head. The average tip-apex distance was twenty-four millimeters (range, nine to sixty-three millimeters) for the successfully treated fractures compared with thirty-eight millimeters (range, twenty-eight to forty-eight millimeters) for those in which the screw cut out (p = 0.0001). None of the 120 screws with a tip-apex distance of twenty-five millimeters or less cut out, but there was a very strong statistical relationship between an increasing tip-apex distance and the rate of cutout, regardless of all other variables related to the fracture.(ABSTRACT TRUNCATED AT 250 WORDS)
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            Intramedullary versus extramedullary fixation for the treatment of intertrochanteric hip fractures.

            One hundred thirty-one patients (135 fractures) who sustained an intertrochanteric fracture were assigned randomly to treatment with either a sliding hip screw or an intramedullary hip screw and followed up prospectively. In patients with unstable intertrochanteric fractures, the intramedullary device was associated with 23% less surgical time and 44% less blood loss; however, use of the intramedullary hip screw in patients who had a stable fracture pattern required 70% greater fluoroscopic time. Intraoperative complications occurred exclusively in patients in the intramedullary hip screw group. There were no differences in the rates of functional recovery between the two fixation groups.
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              The new proximal femoral nail antirotation (PFNA) in daily practice: results of a multicentre clinical study.

              The treatment of unstable trochanteric femoral fractures is still challenging. The ideal implant should be easy to handle, allow for immediate full weight-bearing postoperatively and should have sufficient purchase in the femoral head/neck-fragment to limit cut-outs due to varus-deviation and rotation. The proximal femoral nail antirotation (PFNA), designed by AO, is an intramedullary device with a helical blade rather than a screw for better purchase in the femoral head and was tested in a clinical study. Consecutive patients with unstable trochanteric fractures (AO-classification 31.A.2 and A.3 only) were included and followed for 1 year. Primary objectives were assessment of operative and postoperative complications, whereas secondary objectives included surgical details, general complications and final outcome measurements. In 11 European clinics, 315 patients were included and treated with a PFNA. Almost all fractures healed within 6 months. Fifty-six percent of the patients regained the pre-trauma mobility and 18% died within the follow-up period. Forty-six implant-related complications--leading to 28 unplanned re-operations--were recorded, with four acetabular penetrations (three of which were after a new fall on that hip) and seven ipsilateral femoral shaft fractures as the most serious ones. As the joint-penetrations did not resemble the cut-out seen with other implants it is concluded that the PFNA--due to its helical blade--possibly limits the effects of early rotation of the head/neck-fragment in unstable trochanteric fractures and therefore seems currently to be the optimal implant for the treatment of these fractures especially in osteoporotic bone.
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                Author and article information

                Contributors
                Journal
                J Orthop Surg Res
                J Orthop Surg Res
                Journal of Orthopaedic Surgery and Research
                BioMed Central
                1749-799X
                2013
                17 October 2013
                : 8
                : 35
                Affiliations
                [1 ]Fremantle Hospital Orthopaedic Unit, Fremantle Hospital, Level 6, B Block, Alma Street, Fremantle, Western Australia 6160, Australia
                [2 ]Orthopaedic Surgery, Fremantle Hospital, University of Western Australia, Crawley, Western Australia 6009, Australia
                [3 ]Fremantle and Kaleeya University Hospitals, East Fremantle, Western Australia 6158, Australia
                Article
                1749-799X-8-35
                10.1186/1749-799X-8-35
                3853127
                24135331
                817b7f30-a000-430a-805a-a07e4262eeaf
                Copyright © 2013 Nikoloski et al.; licensee BioMed Central Ltd.

                This is an open access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 23 June 2013
                : 24 September 2013
                Categories
                Research Article

                Surgery
                proximal,femur,fracture,intramedullary,nail,fixation,pfna,tad
                Surgery
                proximal, femur, fracture, intramedullary, nail, fixation, pfna, tad

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