Blog
About

  • Record: found
  • Abstract: found
  • Article: not found

Value of fine-needle aspiration in the diagnosis of Hürthle cell neoplasms.

Head & Neck

pathology, Adenoma, Adolescent, Adult, Aged, Aged, 80 and over, Biopsy, Needle, Carcinoma, Cell Nucleus, ultrastructure, Cytodiagnosis, Diagnosis, Differential, Female, Goiter, Nodular, Humans, Male, Middle Aged, Neoplasm Invasiveness, Sensitivity and Specificity, Thyroid Neoplasms, Thyroiditis, Autoimmune

Read this article at

ScienceOpenPubMed
Bookmark
      There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

      Abstract

      The cytologic and histologic slides on all patients with a diagnosis of Hürthle cell tumor at Mount Sinai Hospital during the last 12 years were reviewed. There were 67 Hürthle cell tumors of which 15 (22%) were malignant. Four carcinomas (27%) occurred in a background of thyroiditis. Forty-three patients with Hürthle cell tumors had undergone preoperative fine-needle aspiration, of which 31 had satisfactory aspirates. For Hürthle cell neoplasia, fine-needle aspiration cytology had a sensitivity of 83.8% (26 of 31) and positive predictive value of 93% (26 of 28), provided that the aspirate was of adequate cellularity. All 3 cases predicted as Hürthle cell carcinoma on the basis of cellular and nuclear atypia were correctly predicted, but 3 carcinomas composed of bland cells were incorrectly predicted as adenomas. We conclude that aspiration cytology can differentiate nonneoplastic from neoplastic Hürthle cell lesions with high accuracy, but that the differentiation between benign and malignant lesions is less reliable.

      Related collections

      Author and article information

      Journal
      8360056

      Comments

      Comment on this article