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      Doppler Echocardiographic Estimation of the Pressure Gradient in Aortic Stenosis

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          Abstract

          This study included 249 consecutive patients with suspected significant aortic valve stenosis. Using contemporary ultrasound equipment we reassessed the value of out-patient Doppler-derived maximum pressure gradients for the prediction of peak-to-peak pressure gradients measured later at heart catheterization. It was possible to record the pressure gradient in 97% of the patients by Doppler examination and in 86% at heart catheterization. There was a fair, statistically significant correlation between Doppler and invasive gradients (n = 201, r = 0.80, p < 0.05, SEE = 21 mm Hg), independent of coexistent aortic regurgitation, atrial fibrillation, left ventricular function, number of days between the examinations and other variables analysed. A Doppler gradient > 80 mm Hg was 98% (90-100%) predictive of critical aortic stenosis (gradient > 50 mm Hg as determined by heart catheterization). Similarly, a Doppler gradient of < 30 mm Hg was 98% (87-100%) predictive of non-critical stenosis. In the remaining patients (53% of the population) the Doppler gradient did not contribute decisively to clinical management.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1996
          1996
          19 November 2008
          : 87
          : 6
          : 545-551
          Affiliations
          Department of Cardiology B, Aarhus University Hospital, Aarhus-Skejby, Denmark
          Article
          177152 Cardiology 1996;87:545–551
          10.1159/000177152
          8904684
          © 1996 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 7
          Categories
          Noninvasive and Diagnostic Cardiology

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