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      Exposure to Airborne Particles and Volatile Organic Compounds from Polyurethane Molding, Spray Painting, Lacquering, and Gluing in a Workshop

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          Abstract

          Due to the health risk related to occupational air pollution exposure, we assessed concentrations and identified sources of particles and volatile organic compounds (VOCs) in a handcraft workshop producing fishing lures. The work processes in the site included polyurethane molding, spray painting, lacquering, and gluing. We measured total VOC (TVOC) concentrations and particle size distributions at three locations representing the various phases of the manufacturing and assembly process. The mean working-hour TVOC concentrations in three locations studied were 41, 37, and 24 ppm according to photo-ionization detector measurements. The mean working-hour particle number concentration varied between locations from 3000 to 36,000 cm −3. Analysis of temporal and spatial variations of TVOC concentrations revealed that there were at least four substantial VOC sources: spray gluing, mold-release agent spraying, continuous evaporation from various lacquer and paint containers, and either spray painting or lacquering (probably both). The mold-release agent spray was indirectly also a major source of ultrafine particles. The workers’ exposure can be reduced by improving the local exhaust ventilation at the known sources and by increasing the ventilation rate in the area with the continuous source.

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          Most cited references56

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          Size, source and chemical composition as determinants of toxicity attributable to ambient particulate matter

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            Respiratory effects are associated with the number of ultrafine particles.

            The association between fine and ultrafine particles and respiratory health was studied in adults with a history of asthma in Erfurt, Eastern Germany. Twenty-seven nonsmoking asthmatics recorded their peak expiratory flow (PEF) and respiratory symptoms daily. The size distribution of ambient particles in the range of 0.01 to 2.5 microm was determined with an aerosol spectrometer during the winter season 1991-1992. Most of the particles (73%) were in the ultrafine fraction (smaller than 0.1 microm in diameter), whereas most of the mass (82%) was attributable to particles in the size range of 0.1 to 0.5 microm. Because these two fractions did not have similar time courses (correlation coefficient r = 0.51), a comparison of their health effects was possible. Both fractions were associated with a decrease of PEF and an increase in cough and feeling ill during the day. Health effects of the 5-d mean of the number of ultrafine particles were larger than those of the mass of the fine particles. In addition, the effects of the number of the ultrafine particles on PEF were stronger than those of particulate matter smaller than 10 microm (PM10). Therefore, the present study suggests that the size distribution of ambient particles helps to elucidate the properties of ambient aerosols responsible for health effects.
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              Toxicology of nanoparticles.

              While nanotechnology and the production of nanoparticles are growing exponentially, research into the toxicological impact and possible hazard of nanoparticles to human health and the environment is still in its infancy. This review aims to give a comprehensive summary of what is known today about nanoparticle toxicology, the mechanisms at the cellular level, entry routes into the body and possible impacts to public health. Proper characterisation of the nanomaterial, as well as understanding processes happening on the nanoparticle surface when in contact with living systems, is crucial to understand possible toxicological effects. Dose as a key parameter is essential in hazard identification and risk assessment of nanotechnologies. Understanding nanoparticle pathways and entry routes into the body requires further research in order to inform policy makers and regulatory bodies about the nanotoxicological potential of certain nanomaterials. Copyright © 2011 Elsevier B.V. All rights reserved.
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                Author and article information

                Contributors
                Role: Academic Editor
                Role: Academic Editor
                Journal
                Int J Environ Res Public Health
                Int J Environ Res Public Health
                ijerph
                International Journal of Environmental Research and Public Health
                MDPI
                1661-7827
                1660-4601
                02 April 2015
                April 2015
                : 12
                : 4
                : 3756-3773
                Affiliations
                [1 ]Department of Physics, University of Helsinki, P.O. Box 48, FI-00014 Helsinki, Finland; E-Mails: tareq.hussein@ 123456helsinki.fi (T.H.); brandon.boor@ 123456helsinki.fi (B.E.B.); kaarle.hameri@ 123456helsinki.fi (K.H.)
                [2 ]Nanosafety Research Centre, Finnish Institute of Occupational Health, Topeliuksenkatu 41 a A, FI-00250 Helsinki, Finland; E-Mails: anna-kaisa.viitanen@ 123456ttl.fi (A.-K.V.); anneli.kangas@ 123456ttl.fi (A.K.); marika.huhtiniemi@ 123456ttl.fi (M.H.); esa.vanhala@ 123456ttl.fi (E.V.); joonas.koivisto@ 123456ttl.fi (A.J.K.)
                [3 ]National Research Centre for the Working Environment, Lersø Parkallé 105, Copenhagen DK-2100, Denmark; E-Mail: stl@ 123456nrcwe.dk
                [4 ]Department of Physics, Faculty of Science, The University of Jordan, Amman, JO-11942, Jordan
                [5 ]Department of Civil, Architectural, and Environmental Engineering, The University of Texas at Austin, Austin, TX 78712, USA
                Author notes
                [* ]Author to whom correspondence should be addressed; E-Mail: bjarke.molgaard@ 123456helsinki.fi ; Tel.: +358-50-318-2442.
                Article
                ijerph-12-03756
                10.3390/ijerph120403756
                4410214
                25849539
                8224b3f0-5950-4007-befc-da3930e769b0
                © 2015 by the authors; licensee MDPI, Basel, Switzerland.

                This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 18 December 2014
                : 24 March 2015
                Categories
                Article

                Public health
                ultrafine particles,particle size distribution,voc,workplace aerosols,polyurethane molding,spray painting,occupational exposure,pid

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