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      Mfold web server for nucleic acid folding and hybridization prediction

      Nucleic Acids Research

      Oxford University Press (OUP)

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          Abstract

          The abbreviated name, 'mfold web server', describes a number of closely related software applications available on the World Wide Web (WWW) for the prediction of the secondary structure of single stranded nucleic acids. The objective of this web server is to provide easy access to RNA and DNA folding and hybridization software to the scientific community at large. By making use of universally available web GUIs (Graphical User Interfaces), the server circumvents the problem of portability of this software. Detailed output, in the form of structure plots with or without reliability information, single strand frequency plots and 'energy dot plots', are available for the folding of single sequences. A variety of 'bulk' servers give less information, but in a shorter time and for up to hundreds of sequences at once. The portal for the mfold web server is http://www.bioinfo.rpi.edu/applications/mfold. This URL will be referred to as 'MFOLDROOT'.

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          Author and article information

          Journal
          Nucleic Acids Research
          Nucleic Acids Research
          Oxford University Press (OUP)
          1362-4962
          July 01 2003
          July 01 2003
          : 31
          : 13
          : 3406-3415
          Article
          10.1093/nar/gkg595
          169194
          12824337
          © 2003

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