9
views
0
recommends
+1 Recommend
2 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Surgical and Clinical Reactivation for Elective Procedures during the COVID Era: A Global Perspective

      research-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Introduction The COVID-19 pandemic has certainly been an unprecedented time. We have had to halt and modify our lives on a local, national, and international level and cooperate to fight this “invisible enemy” in every sector (medical, governmental, industrial, economic, educational, and social). Our immediate action in AAGL has been to organize weekly webinars on subjects related to the pandemic and unite with 8 other professional women's health care societies to provide joint statements that guide our membership and others to expand their knowledge and optimize patient care during the COVID-19 crisis. This international and multidisciplinary collaboration with surgeons and medical specialists at the leading edge of the pandemic course has been an invaluable resource for global health care providers who are at earlier points on the COVID curve. COVID-19 preparedness has required flexibility due to lack of diagnostic tools to accurately detect all viral carriers and absence of effective viral therapy. Most gynecologists have halted the majority of “non-essential” office and surgical procedures in an effort to protect and mitigate risk for all patients and caregivers, preserve personal protective equipment (PPE), and maintain facility capacity for a surge in COVID-19 cases. Joint statements from the American College of Surgeons and the consortium of 9 women's health care societies have provided guidance for resuming surgical practice and reintroducing elective procedures [1-2]. This special article provides further detailed information necessary for successful surgical and clinical reactivation for elective procedures during the COVID Era while the SARS-CoV-2 virus remains a viable threat. Economic Impact of COVID-19 in Healthcare Financial issues impact the reopening of elective surgical services during the COVID-19 pandemic. Decreased surgical volume has led to a widespread and immediate revenue loss on physicians and surgeons in private practice. The loss of volume has a projected longer-term impact on physicians employed by larger groups or institutions and on the facilities themselves. Disruption of the supply chain also limits return to normalcy. PPE is in high demand, and some small centers are unable to order supplies due to allocation of PPE to large hospitals and to areas with higher infection density. Long-term ventilator use has created a national shortage on medications such as opiates and paralytic agents. While hospitals and ambulatory surgical centers are slowly booking surgical cases, the limited supplies, longer room turnover times, and backlogs of cases are projected to lead to salary reductions, layoffs, and financial distress. Timing for Reactivation of Non-essential Office and Surgical Procedures Multiple factors influence the timing of reactivation for non-essential surgery. The burden on the healthcare system and reserve capacity limit reactivation of non-essential office and surgical procedures. Chinese data suggest that an appropriate level of hospital resources must be preserved to care for patients with COVID-19 related illness. The mortality of COVID-19 in Wuhan, where preparedness was not feasible for obvious reasons, was five times higher than in the rest of continental China, where advanced planning made resources more widely available and the hospital systems were not overwhelmed [3]. Social distancing of patients and health care workers to limit viral transmission is another factor in determining the timing of re-entry. Primary care consults increase the proximity and circulation of healthcare professionals and patients, which in turn facilitates viral spread. Such visits have, so far, been deferred for being seen as non-essential in the short term in order to decrease the dissemination of the virus[4]. Conversely, empty hospitals risk bankruptcy before demand comes; furloughed healthcare professionals are already the second most in need of unemployment insurance in some areas[4]. Therefore, a precise modelling method for the pandemic progression is urgently needed. Real time modelling of the COVID instantaneous reproduction rate [3] is essential to predict the curve in the short term and anticipate the need for healthcare resources, preparing for a likely second wave [5]. Adequate modeling and widespread testing allowed for Germany to minimize COVID-19 mortality rates and its impact on the economy [6]. Likewise, with good strategy, institutions have the ability to increase non-COVID care and reactivate elective surgical practice and office procedures. In that sense, timing for resuming elective surgical and clinical care should be determined and monitored by a committee of local authorities, clinical leaders, and hospital administration to assess local viral prevalence, regional success of “flattening the curve,” testing capability, non-COVID care capacity, and PPE supply chain. Experience in continental China shows that a second wave is almost inevitable [3,5]. Consequently, careful planning of healthcare resources should take into account a good safety margin for institutional functional reserve. Therefore, local medical and governmental authorities must collaborate to continuously monitor the pandemic's local reproduction rate, determine the hospital's reserve capacity, and develop modelling strategies to continually guide opening, closing, accelerating, or reducing elective clinical and surgical activity. Case prioritization and scheduling Surgery is considered "elective" or “non-essential” in patients with chronic problems when the procedure can be delayed without significant harm to the patient and without significant change in the prognosis. Although the need for surgery is debatable when pain or functional impairment detracts from quality of life, the determining principle for non-essential surgery is that delay of treatment does not significantly impact clinical outcomes [7].With this in mind, successful reactivation requires clear prioritization criteria aimed to ensure resource optimization and service to the most patients possible. Therefore, during re-entry, outpatient or same-day procedures should be favored over more complex cases in order to preserve hospital resources and decrease the risk of patient exposure. Table 1 summarizes our suggested prioritization scoring system, adapted from Prachand [8]. In this system, the lower the score the higher the priority. Table 1- Suggested prioritization criteria (adapted from Prachand et al, 2020) Table 1- Procedure Factors Score 1 2 3 4 5 OR time (min) <30 31-30 61-120 121-180 ≥180 Estimated LOS Outpatient <24h 24-48h 2-3d ≥4d Risk of Postoperative ICU Very unlikely <5% 5%-10% >10%-25% >25% Anticipated blood loss (mL) <100 100-250 250-500 500-750 >750 Surgical team size (n) 1 2 3 4 >4 Intubation probability (%) < 1-5 6-10 11-25 >25 Surgical site/access None of the following Abdominopelvic MIS Abdominopelvic open surgery, infraumbilical Abdominopelvic open surgery, supraumbilical OHNS/upper GI/thoracic Disease Factors Nonoperative option effectiveness None available Available, <40% as effective as surgery Available, 40% to 60% as effective as surgery Available, 61% to 95% as effective as surgery. Available, 96% to ass effective as surgery Nonoperative treatment option resource/ exposure risk Significantly worse/not applicable Somewhat worse Equivalent Somewhat better Significantly better Impact of 2-wk delay in treatment outcome Significantly worse Worse Moderately worse Slightly worse No worse Impact of 2-wk delay in surgical difficulty/risk Significantly worse Worse Moderately worse Slightly worse No worse Impact of 6-wk delay in treatment outcome Significantly worse Worse Moderately worse Slightly worse No worse Impact of 6-wk delay in surgical difficulty/risk Significantly worse Worse Moderately worse Slightly worse No worse Patient Factors Age (yrs) ≤20 21-40 41-50 51-65 >65 Lung disease (asthma, COPD, CF) None – – Minimal (rare inhaler) > Minimal Obstructive sleep apnea Not present – – Mild/Moderate (no CPAP) On CPAP CV Disease (HTN, CHF, CAD) None Minimal (no meds) Mild (1 med) Moderate (2 meds) Severe (≥3 meds) Diabetes None – Mild (no meds) Moderate (PO meds only) > Moderate (insulin) Immunocompromised* No – – Moderate Severe ILI symptoms (fever, cough, sore throat, body aches, diarrhea) None (Asymptomatic) – – – Yes Exposure to known COVID-19 positive person in past 14 days No Probably not Possibly Probably Yes ⁎ Hematologic malignancy, stem cell transplant, solid organ transplant, active/recent cytotoxic chemotherapy, anti-TNFa or other immunosuppressants, >20 mg prednisone equivalent/day, congenital immunodeficiency, hypogammaglobulinemia on intravenous immunoglobulin, AIDS. CAD, coronary artery disease; CF, cystic fibrosis; CHF, congestive heart failure; COVID-19, novel coronavirus; CPAP, continuous positive airway pressure; CV, cardiovascular; HTN, hypertension; ILI, influenza-like illness; med, medication; PO, by mouth;GI,gastrointestinal;LOS,lengthofstay;MIS,minimallyinvasivesurgery;OHNS,otolaryngology,head&necksurgery;OR,operatingroom Surgical expertise also contributes to mitigation of risk, with shorter operating times, fewer complications, and fewer readmissions observed in high volume centers [9,10,11]. Therefore, the ideal prioritization for allocation of operating room resources involves high volume surgical teams with limited learners performing primarily minimally invasive outpatient procedures [12]. Conservative management and postponement of surgery, when applicable, should be mandatory during the reactivation process, in order to allow for prioritized surgical treatment of those who have already failed non-surgical alternatives. Recommendations for Phases of Surgical Care All caregivers and healthcare systems will have to learn how to co-exist with COVID once the decision is made to resume clinical and surgical practice. Therefore, specific considerations apply to each phase of perioperative care. Preoperative Phase All patients who decide to proceed with surgery must be informed that there is a risk of contracting COVID-19 as a nosocomial infection, resulting in greater morbidity and mortality (see below). Advanced directives and post-surgery rehabilitation should be discussed virtually so that the appropriate forms, paperwork, and pre-authorizations are completed. Institutions can consider electronic signatures and verbal consents, and all details should be documented in the electronic medical record. In institutions that require signature by written paper consent, signatures should be obtained upon admission to avoid non-essential in-person visits. Processes to minimize interpersonal contact are essential during preoperative care. Only strictly essential in-person interactions should be permitted in order to mitigate risks for both patients and caregivers. Preoperative requirements should be streamlined so that the majority of steps are accomplished by physician extenders using distance healthcare or online tools. Preoperative education should not require face-to-face interaction. While local guidelines may vary, US federal guidelines allow the preoperative history to be performed virtually within 30 days of a procedure, and an updated physical examination can be performed at the time of pre-anesthesia care unit admission. When in-person consultations are unavoidable, patient care areas should be disinfected immediately after use. Thorough disinfection is important because the SARS CoV-2 virus can be transmitted by respiratory aerosol droplets, close contact, and fecal-oral transmission. Therefore, extra time should be allotted per visit to allow for sanitizing work areas and patient rooms after each patient visit. The facility waiting rooms and examination rooms should be reorganized to optimize social distancing. Patient check-in should be done by smartphone, smart devices, or kiosks that are far from the person assisting at the front desk, and appropriate PPE and/or aerosolization barriers should be used to separate health care personnel and patients. Screening questions should be routinely utilized to identify COVID-19 symptoms. If a patient screens positive for COVID-19 symptoms, she is directed to local COVID-specific clinics (see section on recommended testing below). Laboratory testing should be consolidated to decrease unnecessary patient exposure during lab visits, and preoperative laboratory tests can be drawn at the time of COVID-specific testing. If available, patient-administered tests to rule out COVID can be obtained at home so that the patient's COVID status is known prior to obtaining preoperative labs [13]. A useful algorithm for preoperative decision making is demonstrated in Figure 1 . [14] Figure 1 – COVID-19 Preoperative Surgery Decision Tree (Courtesy of Cleveland Clinic[14]) Figure 1 Immediate Preoperative and Intraoperative Phases After preoperative procedures have ruled out COVID just prior to surgery (see below), the patient may proceed to scheduled surgery. The number of support people accompanying the patient should be limited to one individual if institutional policy allows. This support individual is required to wear a mask and maintain social distancing etiquette. In certain hospitals where patient support people are forbidden, patient status updates are reported by phone or another telecommunication process. Enhanced Recovery after Surgery (ERAS) [15] protocols should be utilized to optimize intraoperative and postoperative courses. Preoperative and intraoperative surgical checklists should be modified using COVID-19 precautions. Providers should employ the equipment deemed appropriate by their respective institutions. It is recommended that anyone working in the operating room utilize full PPE, which includes shoe covers, impermeable gowns, surgical or N-95 masks, protective head covering, gloves, and eye protection. [16] In the operating room and during surgery, considerations should include air flow and containment or reduction of personnel exposure to respiratory droplets during intubation and extubation. Considerations include using the “intubation box” originally designed by Dr. Hsien Yung Lai in Taiwan [17]; the design is now available in the US [18] and was recently been shown to be a viable solution for reduction of respiratory droplet exposure [19]. In addition, movement of personnel in and out of the operating room should be strictly limited, with efforts made to limit staff breaks mid-case when possible. Trainee participation should be limited and include only personnel essential to the safe performance of the operation in order to avoid exposure and preserve PPE resources [12]. Theoretical concerns pertain to operative technique and relate to viral contamination in the operative field from the smoke plume generated by electrosurgery. Viral particles have been reported in the aerosolized smoke plume created in electrosurgery and the tools and techniques used in surgery can create particles of various sizes [20-23]. While smoke filtration and evacuation are highly recommended during surgery as part of risk mitigation technique, most smoke evacuators remove up to 88% of small particles. To further reduce the aerosolization risk of viral particles (20-360nm), use of active suction is recommended prior to tissue removal, port exchange, and for desufflation at the conclusion of laparoscopic surgery. In addition, electrostatic charging of the peritoneal cavity can precipitate over 99% of particulate matter ranging from 7nm-10um in diameter. Such systems deliver a negative electrostatic charge from an ion wand to generate precipitation (e.g. Ultravision®, Alesi Surgical®). This combination of techniques may be considered for maximum risk mitigation. Postoperative and Post-discharge Phases Optimal facility design incorporates separation of recovery areas for COVID-positive and COVID-negative patients. ERAS protocols should be carried out to optimize same day discharge. A follow up plan should include standardized surveillance and use of distance health, or telemedicine. Patients should not require a face to face visit unless there are complications that require physical examination. COVID home monitoring programs should be used as deemed appropriate; these include: automated thermometers, blood pressure monitors, oximeters, and/or smart device innovations [24]. Patients who have COVID-positive family members should quarantine themselves in local facilities. Some institutions provide such housing opportunities for patients and/or caregivers. Recommended COVID 19 testing within various facilities based on timing of procedures Data from apparent COVID-negative patients after elective surgery suggests that advanced age, comorbidities, surgical time, and surgical complexity may be risk factors for poor prognosis in the event of postoperative development of SARS-CoV2. Such patients are at greater risk of ICU admission (44% vs 26%) than paired patients who did not undergo surgery [25]. Therefore, adequate preoperative screening and diagnosis of COVID-19 infection is essential for the success of any surgical reactivation program. In areas with more than 40 active cases / 100 thousand inhabitants * (see observation at the end of chapter), we suggest that all patients planning to undergo surgery should have a diagnostic test for COVID-19 up to 72 hours before surgery and be quarantined until the time of hospital admission. The RT-PCR test is considered the gold standard for the diagnosis of COVID-19. In clinical practice its specificity varies between 93% and 98%, but sensitivity can vary significantly from 63% to almost 100%, depending on the prevalence, onset of symptoms, viral dynamics, collection method of the clinical specimen, and transport media [26, 27]. Therefore, the positive and negative predictive value of RT-PCR is high for symptomatic patients, but its accuracy may be limited in asymptomatic patients. Other methods that can be used for the diagnosis of COVID-19 include detection of IgA, IgG, and IgM antibodies by enzyme-linked immunosorbent assay (ELISA) and immunochromatography. Initial validation demonstrates a high positive predictive value. The presence of IgG antibodies confirms previous COVID-19 disease [28], suggesting that serological IgG testing may be useful for screening, but not triage for surgery. To date, no data exist that positive IgG antibodies confer lasting immunity to SARS CoV-2. There is no formal indication for chest tomography (CT) as a screening method in asymptomatic patients. However, some COVID-free institutions in Europe and China recommend its use in exceptional situations in high prevalence areas, based on the capability for diagnosis in 54% of asymptomatic cases [29]. Chest CT performed up to 24 hours prior to hospitalization is therefore considered an option when more accurate tests are not available. If surgery is considered mandatory and diagnostic tests are neither available nor reliable, the patient may be quarantined for 14 days prior to surgery (if possible). This recommendation is based on the CDC statement that the incubation period of SARS-CoV-2 and other coronaviruses ranges from 2–14 days[30]. For this strategy to work, patients need to comply with self-isolation and be instructed regarding development of symptoms. If the patient is asymptomatic and tests negative for COVID-19, surgery can be performed with the use of conventional PPE by the surgical team[31]. Guidelines for protection should follow individual institutional standards developed in conjunction with the infection control team. If the patient is symptomatic or has a positive RT-PCR, IgM antibody, or chest CT findings consistent with COVID, the procedure must be postponed, and the patient should be referred based on institutional COVID diagnostic and treatment protocols. Surgical rescheduling should require clinical improvement, normalization of chest CT scan, and two negative RT-PCR tests to confirm resolution[32]. Finally, if RT-PCR, rapid serological testing, or chest CT are not available, elective surgery should only be considered if regional prevalence is less than 40 active cases / 100 thousand inhabitants. In this case, guidelines for the use of PPE should be the same as for COVID-19 positive patients. Regarding concerns about a resurgence of COVID-19, it is imperative that a centralized monitoring system collects data on the number of COVID-positive, asymptomatic patients in a large healthcare system or defined geographical area. Any rise in the number of asymptomatic COVID-positive individuals among elective surgery patients could be a sign of an impending second wave of COVID-19. It is well known that asymptomatic and pre-symptomatic patients are a major source of community transmission. [34,35] According to Robert Redfield, the director of the Centers for Disease Control and Prevention, 25 percent of people infected with SARS CoV-2 are asymptomatic; however, they can still transmit the illness to others.[36] Control of COVID-19 is a dynamic and fluid process. Institutions must be flexible in responding and implementing changes in strategies based on the most current assessment of disease prevalence in the community. As we resume non-essential surgeries, we must be cognizant of the need to adjust and adapt according to the disease burden in the community. As prevalence of COVID-19 decreases in the community, a standardized epidemiological screening questionnaire should be conducted at a minimum. If the epidemiological questionnaire is positive, a RT-PCR and a chest CT can be performed.[29,31] Some countries are employing novel population-based techniques, such as QR code scanning, to facilitate detection of patient exposure to COVID and contact tracing [37]. Financial support to mitigate the impact of reduced surgical volumes Despite the strategies summarized above, the revenue generated by healthcare systems is anticipated to remain at much lower levels than usual due to the mandated halting of non-essential procedures. While reactivation will achieve some normalcy, a second or third wave of viral infection may further decrease revenue generation. Therefore, knowledge of available financial support programs is paramount to ensuring the survival of surgical services. In the United States, the Coronavirus Aid, Relief, and Economic Securities (CARES) Act includes multiple lending programs for physicians and businesses treating patients. These lending programs include the Small Business Association (SBA) Payroll Protection Plan (PPP), Economic Injury Disaster Loans (EIDL), and Department of Health and Human Services (HHS) relief. These programs are summarized on the American Medical Association's website[38]. Businesses with under 500 employees can apply for relief in a forgivable interest-free loan when the funds are used per SBA guidelines. Many physicians in private practice, small group settings, and large group settings qualify for such relief [39]. As surgeons and facilities move toward the “new normal” of pandemic recovery, the number of unemployed workers in the US and abroad will undoubtedly have an impact on insurance coverage. Insurance companies and hospitals will be looking for relief and will be forced to find ways to offset the profound economic implications brought on by the costs associated with COVID-19. It is imperative for physicians everywhere to gain an awareness of these issues and prepare for potential impact on revenue, salary, and job security. Conclusion In our lifetime, the practice of medicine has never been altered to the extent imposed by the COVID-19 pandemic. We, as surgeons, have had to rise up to many challenges in order to meet the needs of our patients while mitigating risk to all those involved in their care. The postponement of non-essential surgical procedures in order to preserve resources has created back logs in our practices that we must address as we co-exist with COVID. The AAGL has forged important collaborations among national and international experts and societies to educate caregivers worldwide during this unprecedented time. This article should serve as a supplemental guide for effective reactivation to clinical and surgical practice to optimize care for the women whom we serve. References 1. Joint Statement: Roadmap for Resuming Elective Surgery after COVID-19 Pandemic. ACS, ASA, AORN, AHA https://www.asahq.org/about-asa/newsroom/news-releases/2020/04/joint-statement-on-elective-surgery-after-covid-19-pandemic. April 17,2020. Accessed on April 17,2020. 2. Joint Statement on Re-introduction of Hospital and Office-based Procedures in the COVID-19 Climate for the Practicing Urogynecologist and Gynecologist. SGS, AAGL, ASRM, AUGS, IGCS, SFP, SGO, SRS. https://www.sgsonline.org/joint-statement-on-re-introduction-of-hospital-and-office-based-procedures-in-the-covid-19-climate April 28, 2020. Accessed on 4/28/2020 3. Leung K, Wu JT, Liu D, Leung GM. First-wave COVID-19 transmissibility andseverity in China outside Hubei after control measures, and second-wave scenario planning: a modelling impact assessment. Lancet. 2020 Apr 25; 395(10233):1382-1393. doi: 10.1016/S0140-6736(20)30746-7. 4. Cuttler D, 2020. https://jamanetwork.com/channels/health-forum/fullarticle/2764547 5. Xu S, Li Y. Beware of the second wave of COVID-19. Lancet. 2020 Apr 25;395(10233):1321-1322. doi: 10.1016/S0140-6736(20)30845-X. 6. Giovanni Legorano & Tom Fairless, 2020 https://www.wsj.com/articles/coronavirus-widens-europes-north-south-economic-divide-11588069310 7. Guy DK, Bosco JA, Savoie FH. AAOS Guidelines for Elective Surgery During the COVID-19 Pandemic. https://www.aaos.org/about/covid-19-information-for-our-members/aaos-guidelines-for-elective-surgery/. Accessed on April 30, 2020 8. Prachand VN, Milner R, Angelos P, Posner MC, Fung JJ, Agrawal N, Jeevanandam V, Matthews JB. Medically Necessary, Time-Sensitive Procedures: Scoring System to Ethically and Efficiently Manage Resource Scarcity and Provider Risk During the COVID-19 Pandemic. J Am Coll Surg. 2020 Apr 9. pii: S1072-7515(20)30317-3. doi:10.1016/j.jamcollsurg.2020.04.011. 9. Bristow RE, Zahurak ML, Diaz-Montes TP, Giuntoli RL, Armstrong DK. Impact of surgeon and hospital ovarian cancer surgical case volume on in-hospital mortality and related short-term outcomes. Gynecol Oncol. 2009 Dec;115(3):334-8. doi: 10.1016/j.ygyno.2009.08.025. 10. Sung VW, Rogers ML, Myers DL, Clark MA. Impact of hospital and surgeon volumes on outcomes following pelvic reconstructive surgery in the United States. Am J Obstet Gynecol. 2006 Dec;195(6):1778-83. 11. Schmidt CM, Turrini O, Parikh P, House MG, Zyromski NJ, Nakeeb A, Howard TJ, Pitt HA, Lillemoe KD. Effect of hospital volume, surgeon experience, and surgeon volume on patient outcomes after pancreaticoduodenectomy: a single-institution experience. Arch Surg. 2010 Jul;145(7):634-40. doi: 10.1001/archsurg.2010.118. 12. COVID-19: AAGL, AUGS, IGCS, SGS, SGO & CanSAGE Joint Statement on Minimally Invasive Gynecologic Surgery. https://www.aagl.org/news/covid-19-joint-statement-on-minimally-invasive-gynecologic-surgery/. Accessed on May 1, 2020. 13. Rosenfield R. Re-Entry: Introducing Safety Protocols into an Ambulatory Surgical Setting In: AAGL COVID-19 Webinar Series: Resuming Elective Surgeries after the COVID-19 pandemic: Global perspectives. https://surgeryu.com/public/covid19043020. Accessed on April 30. 2020. 14. COVID-19 Preoperative Surgery Decision Tree courtesy of the Surgical Reactivation Task Force, Cleveland Clinic, Cleveland, OH. http://portals.ccf.org/occ/Infection-Prevention/Coronavirus-Disease-2019-COVID-19#13854213898-coronavirus-disease-2019-covid-19-toolkit Accessed May 2, 2020. 15. Bache B, Hübner M, Jurt J, Demartines N, Grass F. Minimally invasive surgery and enhanced recovery after surgery: The ideal combination? J Surg Oncol. 2017 Oct;116(5):613-616. doi: 10.1002/jso.24787. 16. Zhu L. Restarting Elective Surgeries in China. In: AAGL COVID-19 Webinar Series: Resuming Elective Surgeries after the COVID-19 pandemic: Global perspectives. https://surgeryu.com/public/covid19043020. Accessed on April 30. 2020. 17. Lai HY. Aerosol Box. 2020. https://sites.google.com/view/aerosolbox/home?authuser=0. Accessed on May 3, 2020 18. Thalia Capos, https://www.thaliacapos.com/pages/thaliabox. Accessed on May 3 2020. 19. Canelli R, Connor CW, Gonzalez M, Nozari A, Ortega R. Barrier enclosure during endotracheal intubation. New England Journal of Medicine 2020. Epub 3 April. doi.org/10.1056/NEJMc2007589 20. Heniford T, Deereberg E, Shao J. Pro-Laparotomy: Surgical Debate in the COVID-19 Pandemic. In: AAGL COVID 19 - Webinar # 3 - Minimally Invasive Surgery versus Laparotomy in the Era of COVID-19: Algorithm, Technology Aspects and Options. https://surgeryu.com/detail/5132 21. Morris SN, Fader AN, Milad MP, Dionisi HJ. Understanding the "Scope" of the Problem: Why Laparoscopy Is Considered Safe during the COVID-19 Pandemic. J Minim Invasive Gynecol. 2020;27(4):789‐791. doi:10.1016/j.jmig.2020.04.002 22. Cohen SL, Liu G, Abrao M, Smart N, Heniford T. Perspectives on Surgery in the Time of COVID-19: Safety First. J Minim Invasive Gynecol. 2020;27(4):792‐793. doi:10.1016/j.jmig.2020.04.003 23. Brown J. Surgical Decision Making in the Era of COVID-19: A New Set of Rules. J Minim Invasive Gynecol. 2020;27(4):785‐786. doi:10.1016/j.jmig.2020.04.001 24. Coronavirus (COVID-19) Update: FDA Issues Emergency Use Authorization for Potential COVID-19 Treatment. https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-issues-emergency-use-authorization-potential-covid-19-treatment 25. Lei S, Jiang F, Su W, Chen C, Chen J, Mei W, Zhan LY, Jia Y, Zhang L, Liu D, Xia ZY, Xia Z. Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection. EClinicalMedicine. 2020 Apr 5:100331. doi: 10.1016/j.eclinm.2020.100331. 26. Procop G. An Update on the Diagnosis before Performing Elective Surgery. In: AAGL COVID-19 Webinar Series: Resuming Elective Surgeries after the COVID-19 pandemic: Global perspectives. https://surgeryu.com/public/covid19043020. Accessed on April 30. 2020. 27. Guo L, Ren L, Yang S, Xiao M, Chang, Yang F, Dela Cruz CS, Wang Y, Wu C, Xiao Y, Zhang L, Han L, Dang S, Xu Y, Yang Q, Xu S, Zhu H, Xu Y, Jin Q, Sharma L, Wang L, Wang J. Profiling Early Humoral Response to Diagnose Novel Coronavirus Disease (COVID-19). Clin Infect Dis. 2020 Mar 21. pii: ciaa310. doi: 10.1093/cid/ciaa310. 28. Zhao J, Yuan Q, Wang H, Liu W, Liao X, Su Y, Wang X, Yuan J, Li T, Li J, Qian S, Hong C, Wang F, Liu Y, Wang Z, He Q, Li Z, He B, Zhang T, Fu Y, Ge S, Liu L, Zhang J, Xia N, Zhang Z. Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019. Clin Infect Dis. 2020 Mar 28. pii: ciaa344. doi:10.1093/cid/ciaa344. 29. Li M, Lei P, Zeng B, et al. Coronavirus Disease (COVID-19): Spectrum of CT Findings and Temporal Progression of the Disease. Acad Radiol. 2020;27(5):603‐608. doi:10.1016/j.acra.2020.03.003 30. CDC -Clinical Questions about COVID-19: Questions and Answershttps://www.cdc.gov/coronavirus/2019-ncov/hcp/faq.html. Accessed on May 2, 2020. 31. Zhu L. Restarting Elective Surgeries in China. In: AAGL COVID-19 Webinar Series: Resuming Elective Surgeries after the COVID-19 pandemic: Global perspectives. https://surgeryu.com/public/covid19043020. Accessed on April 30. 2020. 32. Scheib S. Covid-19: Impact in New Orleans and my practice. In: AAGL Webinar # 2 - Gynecologic Surgery during the COVID-19 Pandemic - Keeping Patients and Surgeons Safe. https://surgeryu.com/detail/5130. April 2, 2020. 33. Al-Muharraqi MA. Testing recommendation for COVID-19 (SARS-CoV-2) in patients planned for surgery - continuing the service and 'suppressing' the pandemic [published online ahead of print, 2020 Apr 13]. Br J Oral Maxillofac Surg. 2020;S0266-4356(20)30164-9. doi:10.1016/j.bjoms.2020.04.014 34. Arons MM, Hatfield KM, Reddy SC, et al. Presymptomatic SARS-CoV-2 infections and transmission in a skilled nursing facility. N Engl J Med. DOI: 10.1056/NEJMoa2008457. 35. Gandhi,M, , Yokoe, D, Havlir,D, Asymptomatic Transmission, the Achilles’ Heel of Current Strategies to Control Covid-19, N Engl J Med. DOI: 10.1056/NEJMe2009758 36. NPR Choice page. https://www.npr.org/sections/health-shots/2020/03/31/824155179/cdc-director-on-models-for-the-months-to-come-this-virus-is-going-to-be-with-us?t=1586065796492 (accessed 5 Apr 2020). Perez-Alba E, Nuzzolo-Shihadeh L, Espinosa-Mora JE, Camacho-Ortiz A. Use of self-administered surveys through QR code and same center telemedicine in a walk-in clinic in the era of COVID-19. J Am Med Inform Assoc. 2020 Apr 13. pii: ocaa054. doi: 10.1093/jamia/ocaa054. 37. AMA - COVID-19 (2019 novel coronavirus) resource center for physicians. https://www.ama-assn.org/delivering-care/public-health/covid-19-2019-novel-coronavirus-resource-center-physicians. Accessed on May 2, 2020. 38. US Department of the Treasury. How the Treasury Department is Taking Action - The CARES Act. https://home.treasury.gov

          Related collections

          Author and article information

          Contributors
          Journal
          J Minim Invasive Gynecol
          J Minim Invasive Gynecol
          Journal of Minimally Invasive Gynecology
          AAGL.
          1553-4650
          1553-4669
          22 May 2020
          22 May 2020
          Affiliations
          [1 ]OBGYN and Women's Health Institute, Cleveland Clinic, Desk A-81, 9500 Euclid Avenue, Cleveland, OH 44195, USA
          [2 ]Department of Obstetrics and Gynecology and Levine Cancer Institute at Atrium Health, Charlotte, NC 28204, USA
          [3 ]Gynecologic Division, BP - A Beneficencia Portuguesa de Sao Paulo, Sao Paulo, SP, BR
          [4 ]Department of Obstetrics and Gynecology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, BR
          [5 ]CEDEM Centro de Estudio de la Mujer, Córdoba, Argentina
          [6 ]Pearl Women's Center, Pearl Surgicenter, Portland, OR, USA
          [7 ]Department of Obstetrics, Gynecology & Reproductive Sciences, Pittsburgh, PA, USA
          [8 ]Department of Obstetrics and Gynecology of Mount Sinai Hospital and Women's College Hospital, University of Toronto, Toronto, ON, Canada
          Author notes
          [* ]Corresponding Author: Marie Fidela R. Paraiso, MD, Professor and Vice Chair, OBGYN and Women's Health Institute, Cleveland Clinic, Desk A-81, 9500 Euclid Avenue, Cleveland, OH 44195, USA Paraism@ 123456ccf.org
          Article
          S1553-4650(20)30244-2
          10.1016/j.jmig.2020.05.012
          7242200
          827d2a80-c057-4b08-b5e8-65a6bf1aa1e5
          © 2020 AAGL. All rights reserved.

          Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

          History
          : 4 May 2020
          : 5 May 2020
          Categories
          Article

          Comments

          Comment on this article