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Alzheimer's disease
Author(s):
Clive Ballard
,
Serge Gauthier
,
Anne Corbett
,
Carol Brayne
,
Dag Aarsland
,
Emma Jones
Publication date
Created:
March 2011
Publication date
(Print):
March 2011
Journal:
The Lancet
Publisher:
Elsevier BV
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There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
An estimated 24 million people worldwide have dementia, the majority of whom are thought to have Alzheimer's disease. Thus, Alzheimer's disease represents a major public health concern and has been identified as a research priority. Although there are licensed treatments that can alleviate symptoms of Alzheimer's disease, there is a pressing need to improve our understanding of pathogenesis to enable development of disease-modifying treatments. Methods for improving diagnosis are also moving forward, but a better consensus is needed for development of a panel of biological and neuroimaging biomarkers that support clinical diagnosis. There is now strong evidence of potential risk and protective factors for Alzheimer's disease, dementia, and cognitive decline, but further work is needed to understand these better and to establish whether interventions can substantially lower these risks. In this Seminar, we provide an overview of recent evidence regarding the epidemiology, pathogenesis, diagnosis, and treatment of Alzheimer's disease, and discuss potential ways to reduce the risk of developing the disease. Copyright © 2011 Elsevier Ltd. All rights reserved.
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Alternative approaches to Alzheimer's Disease
Author and article information
Journal
Title:
The Lancet
Abbreviated Title:
The Lancet
Publisher:
Elsevier BV
ISSN (Print):
01406736
Publication date Created:
March 2011
Publication date (Print):
March 2011
Volume
: 377
Issue
: 9770
Pages
: 1019-1031
Article
DOI:
10.1016/S0140-6736(10)61349-9
PubMed ID:
21371747
SO-VID:
828bd699-fe20-438a-b375-cd3211985533
Copyright ©
© 2011
License:
https://www.elsevier.com/tdm/userlicense/1.0/
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