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      Approach towards developing a novel procedure to selectively quantify topically applied substances in the hair follicles of the model tissue porcine ear skin.

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          Abstract

          Hair follicles represent reservoirs for localized drug therapy and transport pathways for systemic drug delivery. This study describes an approach towards developing a novel procedure for quantifying topically applied substances located in the hair follicles of porcine ear skin, a model for human in vivo skin, using a fluorescent dye. Approximately 5% of the topically applied dye was recovered from the hair follicles, which is in accordance with a previous study.

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          Author and article information

          Journal
          Exp. Dermatol.
          Experimental dermatology
          Wiley-Blackwell
          1600-0625
          0906-6705
          Jun 2013
          : 22
          : 6
          Article
          10.1111/exd.12113
          23489479
          829d7b2e-95b8-4f3d-a2b1-2d838b69f3f4
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