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      Androgen Receptor Splice Variant 7 and Efficacy of Taxane Chemotherapy in Patients With Metastatic Castration-Resistant Prostate Cancer.

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          Abstract

          We previously showed that detection of androgen receptor splice variant 7 (AR-V7) in circulating tumor cells (CTCs) from men with castration-resistant prostate cancer (CRPC) was associated with primary resistance to enzalutamide and abiraterone therapy, but the relevance of AR-V7 status in the context of chemotherapy is unknown.

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          Author and article information

          Journal
          JAMA Oncol
          JAMA oncology
          2374-2445
          2374-2437
          Aug 2015
          : 1
          : 5
          Affiliations
          [1 ] Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
          [2 ] Department of Urology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
          Article
          2300763 NIHMS698084
          10.1001/jamaoncol.2015.1341
          26181238

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