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      Changes in renal function during weight loss induced by high vs low-protein low-fat diets in overweight subjects.

      Brain research. Brain research reviews
      Adolescent, Adult, Albuminuria, Body Mass Index, Diet, Fat-Restricted, Diet, Protein-Restricted, Dietary Proteins, administration & dosage, Energy Intake, Female, Glomerular Filtration Rate, Humans, Kidney, pathology, physiopathology, Magnetic Resonance Imaging, Male, Middle Aged, Nitrogen, urine, Obesity, diet therapy, Weight Loss

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          Abstract

          Due to the high satiating effect of protein, a high-protein diet may be desirable in the treatment of obesity. However the long-term effect of different levels of protein intake on renal function is unclear. To assess the renal effects of high vs low protein contents in fat-reduced diets. Randomized 6 months dietary intervention study comparing two controlled ad libitum diets with 30 energy (E%) fat content: high-protein (HP; 25 E%) or low-protein, (LP, 12 E% protein). All food was provided by self-selection in a shop at the department, and high compliance to the diet composition was confirmed by measurements of urinary nitrogen excretion. 65 healthy, overweight and obese (25

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