IN-VITRO SCREENING OF CISSUS QUADRANGULARIS L. VARIANT II AGAINST HELICOBACTER PYLORI

Abstract

Cissus quadrangularis L. variant II belonging to the family Vitaceae was screened for its activity Hellcobacter pylori (Hp) human isolates. Flowering and vegetative period samples were analyzed. Aqueous (hot and cold) and solvent extracts (acetone, chloroform and methanol) were screened. Among them chloroform was observed to recover bioactive principles with low MIC and MLC. MIC and MLC was 40 μg/ml for flowering period. Whereas for vegetative period MIC was 40 μg/ml and MLC was 40 μg/ml respectively. Extracts from samples collected during flowering period were better than that of vegetative period. The results confirm the traditional use of the plant in PUD.