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      Risk factors for post-operative delirium in elderly Chinese patients

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          Abstract

          Objective: The purpose of this study was to systematically analyze the risk factors for post-operative delirium (PD) in elderly patients in an effort to provide a basis for developing relevant clinical interventions in China.

          Methods: All published studies focusing on the risk factors for PD among elderly patients in Wanfant Data, China National Knowledge Infrastructure (CNKI), and VIP were collected according to the inclusion and exclusion criteria of this study. A meta-analysis was performed on case-control studies using RevMan5.2 software, and the incidence of PD risk factors was calculated among case series.

          Results: Sixteen studies, including 8 case-control studies and 8 case series, were included in the current study. There were 353 cases and 2008 controls in the case-control studies. The pooled odds ratios (95% CI) of PD risk factors were as follows: hypoxemia, 2.58 (1.59~4.18); pulmonary infection, 4.51 (2.23~9.13); hypertension, 2.16 (1.20~3.89); coronary heart disease, 1.50 (0.82~2.73); post-operative pain, 3.18 (1.63~6.20); general anesthesia, 3.64 (0.94~14.11); operative time, 1.70 (0.79~3.66); and senility, 0.52 (–0.25~1.29). The meta-analysis showed that hypoxemia, pulmonary infection, hypertension, coronary heart disease, post-operative pain, general anesthesia, operative time, and senility were significant risk factors for PD. There were 404 cases in the case series, and the incidence of hypoxemia, hypertension, general anesthesia, diabetes mellitus, senility, coronary heart disease, pulmonary infection, and cerebrovascular disease was 62.62%, 55.90%, 33.7%, 24.8%, 16.58%, 15.3%, 13.9%, and 12.1%, respectively, which was much higher than other risk factors.

          Conclusion: Senility, hypertension, coronary heart disease, diabetes mellitus, pulmonary infection, hypoxemia, post-operative pain, and general anesthesia are significant risk factors for PD among elderly Chinese patients.

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          Most cited references 28

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          Relationship between pain and opioid analgesics on the development of delirium following hip fracture

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            Analysis of risk factors for delirium in the elderly patients after spinal operation

             H. Li,  CD Li,  XD Yi (2012)
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              Relevant factors of delirium in the elderly patients after spinal operation

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                Author and article information

                Journal
                FMCH
                Family Medicine and Community Health
                FMCH
                Family Medicine and Community Health & American Chinese Medical Education Association (USA )
                xxx-xxx
                2305-6983
                December 2014
                December 2014
                : 2
                : 4
                : 32-40
                Affiliations
                1Nursing Department, Zunyi Medical College Affiliated Hospital, Guizhou 563003, China
                Author notes
                CORRESPONDING AUTHOR: Zhixia Jiang, Nursing Department, Zunyi Medical College Affiliated Hospital, Guizhou 563003, China, E-mail: jzxhl@ 123456126.com
                Article
                fmch20140119
                10.15212/FMCH.2014.0119
                Copyright © 2014 Family Medicine and Community Health

                This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License (CC BY-NC 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc/4.0/.

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                Self URI (journal page): http://fmch-journal.org/
                Categories
                Original Research

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