6
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Amygdala control of emotion-induced forgetting and remembering: evidence from Urbach-Wiethe disease.

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          When presented in a neutral context, emotional items interfere with episodic encoding of temporally contiguous non-emotional items, resulting in dissociable valence-dependent retrograde and arousal-dependent anterograde modulatory effects. By studying two rare patients with congenital lipoid proteinosis (Urbach-Wiethe) and a focal disease emphasis on the basolateral amygdala (BLA), we demonstrate that this bidirectional modification of episodic encoding by emotion depends on the integrity of the amygdala, as both retrograde and anterograde modulatory effects are absent. Our findings implicate the amygdala in a neural circuitry that orchestrates rapid retrograde and anterograde regulation of episodic memory access upon criteria of behavioral significance.

          Related collections

          Author and article information

          Journal
          Neuropsychologia
          Neuropsychologia
          Elsevier BV
          0028-3932
          0028-3932
          Mar 14 2007
          : 45
          : 5
          Affiliations
          [1 ] Department of Psychiatry, University of Bonn, 53105 Bonn, Germany. rene.hurlemann@ukb.uni-bonn.de
          Article
          S0028-3932(06)00343-5
          10.1016/j.neuropsychologia.2006.08.027
          17027866
          8355a6ce-f155-45ee-ac79-f2eebf0810e8

          Comments

          Comment on this article