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      During economic crisis can sleep questionnaires improve the value of oximetry for assessing sleep apnea?

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          Abstract

          Background

          The diagnosis of obstructive sleep apnea/hypopnea syndrome (OSAHS) is essential but polysomnography (PSG) is expensive and time consuming. Oximetry has been used as a less expensive indicator of OSAHS. The aim of the study was to evaluate the clinical utility of the combination of oximetry with four different questionnaires: Stop, Stop Bang (S-B), Berlin questionnaire (BQ), Epworth Sleepiness Scale (ESS) in order to identify patients at risk for OSAHS compared with in-laboratory PSG.

          Methods

          Patients visiting a sleep clinic were prospectively studied. They completed Stop, S-B, BQ and ESS. Home oximetry and in laboratory PSG were performed within 3–20 days.

          Results

          A total of 204 patients were included in the study (77.5% males, mean age 51.8±13.8 years, BMI 32.8±6.2 kg/m 2, SaO 2% awake 95.7±2). S-B had the highest sensitivity (Se) (97.5%) and negative predictive value (NPV) (62.5%) but the lowest specificity (Sp) (9%), whereas ESS had the best Sp (75%) and positive predictive values (PPV) (81.4%). The predictive values of questionnaires improved as the severity of OSAHS worsened. The predictive values of oximetry were high for severe but low for mild and moderate OSAHS. For that oximetry was combined with different sleep questionnaires in different OSAHS severity groups, but with no improvement in the predictive values.

          Conclusions

          Oximetry may be used as a tool for identifying severe OSAHS. For mild and moderate disease the combination of questionnaires did not improve the diagnostic accuracy and especially for symptomatic patients with negative results, the need of PSG is essential.

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          Author and article information

          Journal
          Ann Transl Med
          Ann Transl Med
          ATM
          Annals of Translational Medicine
          AME Publishing Company
          2305-5839
          2305-5847
          November 2016
          November 2016
          : 4
          : 22
          : 443
          Affiliations
          [1 ]Pulmonary Department, “G. Papanikolaou” General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece;
          [2 ]Medical Clinic I, “Fuerth” Hospital, University of Erlangen, Fuerth, Germany;
          [3 ]Ear, Nose and Throat Department, “Saint Luke” Private Hospital, Panorama, Thessaloniki, Greece;
          [4 ]Second Pulmonary Clinic, “Sotiria” Chest Diseases Hospital, Athens 11527, Greece
          Author notes

          Contributions: (I) Conception and design: A Pataka, P Argyropoulou; (II) Administrative support: A Pataka, P Zarogoulidis; (III) Provision of study materials or patients: A Pataka, P Zarogoulidis, P Argyropoulou; (IV) Collection and assembly of data: A Pataka, P Zarogoulidis; (V) Data analysis and interpretation: A Pataka, W Hohenforst-Schmidt, T Tsiouda, D Tsavlis; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors.

          Correspondence to: Paul Zarogoulidis, MD, PhD. Pulmonary Department, “G. Papanikolaou” General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece. Email: pzarog@ 123456hotmail.com .
          Article
          PMC5159387 PMC5159387 5159387 atm-04-22-443
          10.21037/atm.2016.11.06
          5159387
          27999777
          83a4bf86-f114-4b1d-9d88-fff63ff189a4
          2016 Annals of Translational Medicine. All rights reserved.
          History
          : 19 April 2016
          : 01 November 2016
          Categories
          Original Article

          Oximetry,Epworth Sleepiness Scale (ESS),Stop,Stop-Bang (S-B),Berlin questionnaire (BQ),sleep apnea

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