Amniotic Fluid, Maternal and Fetal Blood Insulin in Overweight Pregnant Women

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Abstract

The effect of excessive maternal weight gain on insulin levels during pregnancy (15 cases) was compared with the insulin levels in a control group (20 normal pregnancies) by radio immunologic determination of insulin in the amniotic fluid and in maternal and fetal blood. The mean values of insulin in the control group were as follows: mother 24.9 ± 0.51, fetus 10.86 ± 0.48 and amniotic fluid 6.08 ± 0.42 µU/ml, and in patients with excessive weight gain during pregnancy, maternal insulin mean values were 39.45 ± 1.86, fetal 20.99 ± 3.39 and amniotic fluid 12.25 ± 1.15 µU/ml. Insulin concentrations in maternal blood (P < 0.001), fetal blood (P < 0.001) and amniotic fluid (P < 0.001) were higher in excessive weight gain pregnancies as compared to the control group.

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Journal ID (publisher-id): HRE

Journal ID (nlm-ta): Horm Res Paediatr

Journal ID (doi): 10.1159/issn.1663-2818

Title: Hormone Research in Paediatrics

Publisher: S. Karger AG

ISSN (Print): 1663-2818

ISSN (Electronic): 1663-2826

Publication date Subscription-year: 1978

Publication date (Print): 1978

Publication date (Electronic): 25 November 2008

Volume: 9

Issue: 5

Pages: 249-253

Affiliations

Department of Endocrinology, Medical College of Georgia, Augusta, Ga., and 1st Department of Obstetrics and Gynecology, University of Athens, Athens

Article

Publisher ID: 178920 Other ID: Horm Res 1978;9:249–253

DOI: 10.1159/000178920

PubMed ID: 680636

SO-VID: 83e8a07b-89ae-4095-b896-9b2615628b6c

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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

History

Date received : 24 May 1977

Date accepted : 30 November 1977

Page count

Pages: 5

Amniotic Fluid, Maternal and Fetal Blood Insulin in Overweight Pregnant Women

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Karger: Endocrinology

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