For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
49
views
56
references
 Top references
cited by
84
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    4
    shares
      169
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      A current perspective on antimicrobial resistance in Southeast Asia

      review-article
      Author(s): 1 , 1 , 2 , 2 , 3 , 2 , 3 , 1 , 2 ,   1 , 2 , 4 , on behalf of the Southeast Asia Antimicrobial Resistance Network Members of the Southeast Asia Antimicrobial Resistance Network
      Publication date (Electronic):
      Journal: Journal of Antimicrobial Chemotherapy
      Publisher: Oxford University Press

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Southeast Asia, a vibrant region that has recently undergone unprecedented economic development, is regarded as a global hotspot for the emergence and spread of antimicrobial resistance (AMR). Understanding AMR in Southeast Asia is crucial for assessing how to control AMR on an international scale. Here we (i) describe the current AMR situation in Southeast Asia, (ii) explore the mechanisms that make Southeast Asia a focal region for the emergence of AMR, and (iii) propose ways in which Southeast Asia could contribute to a global solution.

          Related collections

          Most cited references56

          • Record: found
          • Abstract: found
          • Article: not found

          Effect of antibiotic prescribing in primary care on antimicrobial resistance in individual patients: systematic review and meta-analysis.

          Ceire Costelloe, Chris Metcalfe, Andrew Lovering … (2010)
          To systematically review the literature and, where appropriate, meta-analyse studies investigating subsequent antibiotic resistance in individuals prescribed antibiotics in primary care. Systematic review with meta-analysis. Observational and experimental studies identified through Medline, Embase, and Cochrane searches. Review methods Electronic searches using MeSH terms and text words identified 4373 papers. Two independent reviewers assessed quality of eligible studies and extracted data. Meta-analyses were conducted for studies presenting similar outcomes. The review included 24 studies; 22 involved patients with symptomatic infection and two involved healthy volunteers; 19 were observational studies (of which two were prospective) and five were randomised trials. In five studies of urinary tract bacteria (14 348 participants), the pooled odds ratio (OR) for resistance was 2.5 (95% confidence interval 2.1 to 2.9) within 2 months of antibiotic treatment and 1.33 (1.2 to 1.5) within 12 months. In seven studies of respiratory tract bacteria (2605 participants), pooled ORs were 2.4 (1.4 to 3.9) and 2.4 (1.3 to 4.5) for the same periods, respectively. Studies reporting the quantity of antibiotic prescribed found that longer duration and multiple courses were associated with higher rates of resistance. Studies comparing the potential for different antibiotics to induce resistance showed no consistent effects. Only one prospective study reported changes in resistance over a long period; pooled ORs fell from 12.2 (6.8 to 22.1) at 1 week to 6.1 (2.8 to 13.4) at 1 month, 3.6 (2.2 to 6.0) at 2 months, and 2.2 (1.3 to 3.6) at 6 months. Individuals prescribed an antibiotic in primary care for a respiratory or urinary infection develop bacterial resistance to that antibiotic. The effect is greatest in the month immediately after treatment but may persist for up to 12 months. This effect not only increases the population carriage of organisms resistant to first line antibiotics, but also creates the conditions for increased use of second line antibiotics in the community.
          Article 0 comments Cited 325 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Emerging infectious diseases in southeast Asia: regional challenges to control

            Richard Coker, Benjamin Hunter, James W Rudge … (2011)
            Summary Southeast Asia is a hotspot for emerging infectious diseases, including those with pandemic potential. Emerging infectious diseases have exacted heavy public health and economic tolls. Severe acute respiratory syndrome rapidly decimated the region's tourist industry. Influenza A H5N1 has had a profound effect on the poultry industry. The reasons why southeast Asia is at risk from emerging infectious diseases are complex. The region is home to dynamic systems in which biological, social, ecological, and technological processes interconnect in ways that enable microbes to exploit new ecological niches. These processes include population growth and movement, urbanisation, changes in food production, agriculture and land use, water and sanitation, and the effect of health systems through generation of drug resistance. Southeast Asia is home to about 600 million people residing in countries as diverse as Singapore, a city state with a gross domestic product (GDP) of US$37 500 per head, and Laos, until recently an overwhelmingly rural economy, with a GDP of US$890 per head. The regional challenges in control of emerging infectious diseases are formidable and range from influencing the factors that drive disease emergence, to making surveillance systems fit for purpose, and ensuring that regional governance mechanisms work effectively to improve control interventions.
            Article 0 comments Cited 194 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Characteristics and outcomes of public campaigns aimed at improving the use of antibiotics in outpatients in high-income countries.

              Benedikt David Huttner, Herman Goossens, Theo Verheij … (2010)
              The worldwide increase in resistance to antimicrobial drugs has made reducing the unnecessary use of antibiotics a public health priority. There have been campaigns in many countries to educate the public about appropriate use of antibiotics in outpatients. By use of a comprehensive search strategy and structured interviews, we were able to identify and review the characteristics and outcomes of 22 campaigns done at a national or regional level in high-income countries between 1990 and 2007. The intensity of the campaigns varied widely, from simple internet to expensive mass-media campaigns. All but one campaign targeted the public and physicians simultaneously. Most campaigns that were formally evaluated seemed to reduce antibiotic use. The effect on resistance to antimicrobial drugs cannot be assessed accurately at present. Although the most effective interventions and potential adverse outcomes remain unclear, public campaigns can probably contribute to more careful use of antibiotics in outpatients, at least in high-prescribing countries. 2010 Elsevier Ltd. All rights reserved.
              Article 0 comments Cited 158 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Journal ID (nlm-ta): J Antimicrob Chemother
                Journal ID (iso-abbrev): J. Antimicrob. Chemother
                Journal ID (publisher-id): jac
                Title: Journal of Antimicrobial Chemotherapy
                Publisher: Oxford University Press
                ISSN (Print): 0305-7453
                ISSN (Electronic): 1460-2091
                Publication date (Print): November 2017
                Publication date (Electronic): 07 August 2017
                Publication date PMC-release: 07 August 2017
                Volume: 72
                Issue: 11
                Pages: 2963-2972
                Affiliations
                [1 ]The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam
                [2 ]Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, Oxford University, UK
                [3 ]Mahidol-Oxford Tropical Medicine Research Unit (MORU), Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
                [4 ]The London School of Hygiene and Tropical Medicine, London, UK
                Author notes
                [* ]Corresponding author. The Hospital for Tropical Diseases, 764 Vo Van Kiet, Quan 5, Ho Chi Minh City, Vietnam. Tel: +8489241761; Fax: +8489238904; E-mail: sbaker@ 123456oucru.org
                [†]

                Members are listed in the Acknowledgements section.

                Article
                Publisher ID: dkx260
                DOI: 10.1093/jac/dkx260
                PMC ID: 5890732
                PubMed ID: 28961709
                SO-VID: 8495a371-f512-4697-ae7c-4eb1e9e113bb
                Copyright © © The Author 2017. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.
                License:

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Page count
                Pages: 10
                Funding
                Funded by: Wellcome Trust 10.13039/100004440
                Award ID: 110085/Z/15/Z
                Funded by: Wellcome Trust 10.13039/100004440
                Categories
                Subject: Reviews

                ScienceOpen disciplines: Oncology & Radiotherapy
                Data availability:
                ScienceOpen disciplines: Oncology & Radiotherapy

                Comments

                Comment on this article

                scite_

                Similar content169

                See all similar

                Cited by80

                See all cited by