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      Lipid Management in Chronic Kidney Disease: Systematic Review of PCSK9 Targeting

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      Drugs
      Springer Science and Business Media LLC

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          Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease

          Evolocumab is a monoclonal antibody that inhibits proprotein convertase subtilisin-kexin type 9 (PCSK9) and lowers low-density lipoprotein (LDL) cholesterol levels by approximately 60%. Whether it prevents cardiovascular events is uncertain.
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            Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

            The Lancet, 385(9963), 117-171
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              2016 ESC/EAS Guidelines for the Management of Dyslipidaemias.

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                Author and article information

                Contributors
                (View ORCID Profile)
                Journal
                Drugs
                Drugs
                Springer Science and Business Media LLC
                0012-6667
                1179-1950
                February 2018
                January 3 2018
                February 2018
                : 78
                : 2
                : 215-229
                Article
                10.1007/s40265-017-0858-2
                29299849
                84b65104-a1c3-4013-adeb-e967334dfc56
                © 2018

                http://www.springer.com/tdm

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