Comparative analysis is an important goal of the research carried out by the Centre for Urban Networks Evolution. Archaeologists and historians conducting research on cities need comparison for several reasons: to distinguish unique features of individual cities from universal urban traits; to better understand individual cities and deposits; and to generalize about cities, towns, and urbanism. In this article, I review methods and concepts of comparative urban analysis, including systematic vs intensive comparisons, the scale of comparison, synchronic vs diachronic comparison, and comparison at different stages in a research trajectory. I also discuss empirical and epistemological linkages between comparisons of cities and comparisons of urban deposits as studied by high-definition archaeological methods. These issues of comparison can help integrate the analysis of urban networks with high-definition localized studies of urban deposits.