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      Marine-derived fungi as a source of bioactive indole alkaloids with diversified structures

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          Abstract

          Marine-derived fungi are well known as rich sources of bioactive natural products. Growing evidences indicated that indole alkaloids, isolated from a variety of marine-derived fungi, have attracted considerable attention for their diverse, challenging structural complexity and promising bioactivities, and therefore, indole alkaloids have potential to be pharmaceutical lead compounds. Systemic compilation of the relevant literature. In this review, we demonstrated a comprehensive overview of 431 new indole alkaloids from 21 genera of marine-derived fungi with an emphasis on their structures and bioactivities, covering literatures published during 1982–2019.

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          Author and article information

          Journal
          MLST
          Marine Life Science & Technology
          Springer (China )
          2096-6490
          2662-1746
          01 February 2021
          24 November 2020
          : 3
          : 1
          : 44-61
          Affiliations
          [1] 1College of Pharmaceutical Sciences, Institute of Life Science and Green Development, Hebei University, Baoding 071002, China
          Author notes
          *Corresponding author: Fei Cao, E-mail: caofei542927001@ 123456163.com
          Article
          s42995-020-00072-w
          10.1007/s42995-020-00072-w
          37073395
          8592c28e-6762-4bcd-9bb3-0118c189eca5
          © 2020 Ocean University of China
          History
          : 19 May 2020
          : 09 September 2020
          Categories
          Reviews

          Evolutionary Biology,Cell biology,Aquaculture & Fisheries,Ecology,Biotechnology,Life sciences
          Chemical diversity,Marine-derived fungus,Indole alkaloid,Bioactivity

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