Effect of dalteparin administration on thrombin generation kinetics in healthy dogs.

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Abstract

Dalteparin is used to prevent thrombotic complications in dogs. Measurement of anti-factor Xa (anti-FXa) activity is currently used for monitoring therapy, but remains a nonfunctional test. The calibrated automated thrombogram (CAT) could be a suitable approach for functional monitoring.

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Journal

Journal ID (iso-abbrev): Vet Clin Pathol

Title: Veterinary clinical pathology

Publisher: Wiley

ISSN (Electronic): 1939-165X

ISSN (Print): 0275-6382

Publication date (Electronic): Jun 2017

Volume: 46

Issue: 2

Affiliations

[1 ] Department of Pathology and Microbiology, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada.

[2 ] GREPAQ - Department of Veterinary Biomedicine, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada.

[3 ] Department of Clinical Sciences, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada.

Article

DOI: 10.1111/vcp.12489

PubMed ID: 28430367

SO-VID: 85987a83-9cb3-47f0-8c21-2842f1614498

History

Keywords: Coagulation,endogenous thrombin potential,low-molecular-weight heparin,pharmacodynamics

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Keywords: Coagulation, endogenous thrombin potential, low-molecular-weight heparin, pharmacodynamics

Effect of dalteparin administration on thrombin generation kinetics in healthy dogs.

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