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Neutrophil Gelatinase–Associated Lipocalin and Cystatin C Are Sensitive Markers of Renal Injury in Patients With Multiple Myeloma
Gerasimos-Petros Papassotiriou ,
Efstathios Kastritis ,
Maria Gkotzamanidou ,
Dimitrios Christoulas ,
Evangelos Eleutherakis-Papaiakovou ,
Magdalini Migkou ,
Maria Gavriatopoulou ,
Maria Roussou ,
Alexandra Margeli ,
Ioannis Papassotiriou ,
Meletios A. Dimopoulos ,
Evangelos Terpos
January 2016
January 2016
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Abstract
Renal impairment is a common complication of patients with multiple myeloma (MM).
We aimed to evaluate the clinical significance of 2 newly discovered biomarkers of
renal injury, cystatin C (CysC), a protein reflecting glomerular filtration rate,
and neutrophil gelatinase-associated lipocalin (NGAL), a protein reflecting tubular
injuries.