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      Observational Studies: Cohort and Case-Control Studies :

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      Plastic and Reconstructive Surgery

      Ovid Technologies (Wolters Kluwer Health)

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          Abstract

          Observational studies constitute an important category of study designs. To address some investigative questions in plastic surgery, randomized controlled trials are not always indicated or ethical to conduct. Instead, observational studies may be the next best method of addressing these types of questions. Well-designed observational studies have been shown to provide results similar to those of randomized controlled trials, challenging the belief that observational studies are second rate. Cohort studies and case-control studies are two primary types of observational studies that aid in evaluating associations between diseases and exposures. In this review article, the authors describe these study designs and methodologic issues, and provide examples from the plastic surgery literature.

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          Author and article information

          Journal
          Plastic and Reconstructive Surgery
          Plastic and Reconstructive Surgery
          Ovid Technologies (Wolters Kluwer Health)
          0032-1052
          2010
          December 2010
          : 126
          : 6
          : 2234-2242
          Article
          10.1097/PRS.0b013e3181f44abc
          2998589
          20697313
          85d46e24-1dda-45de-bbff-92af52b01dc2
          © 2010

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