Endoscopic optical coherence tomography: technologies and clinical applications [Invited]

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Abstract

In this paper, we review the current state of technology development and clinical applications of endoscopic optical coherence tomography (OCT). Key design and engineering considerations are discussed for most OCT endoscopes, including side-viewing and forward-viewing probes, along with different scanning mechanisms (proximal-scanning versus distal-scanning). Multi-modal endoscopes that integrate OCT with other imaging modalities are also discussed. The review of clinical applications of endoscopic OCT focuses heavily on diagnosis of diseases and guidance of interventions. Representative applications in several organ systems are presented, such as in the cardiovascular, digestive, respiratory, and reproductive systems. A brief outlook of the field of endoscopic OCT is also discussed.

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Author and article information

Journal

Journal ID (nlm-ta): Biomed Opt Express

Journal ID (iso-abbrev): Biomed Opt Express

Journal ID (publisher-id): BOE

Title: Biomedical Optics Express

Publisher: Optical Society of America

ISSN (Electronic): 2156-7085

Publication date (Electronic): 07 April 2017

Publication date Collection: 01 May 2017

Publication date PMC-release: 07 April 2017

Volume: 8

Issue: 5

Pages: 2405-2444

Affiliations

[1 ]Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA

[2 ]ICube Laboratory, CNRS, Strasbourg University, 1 Place de l’Hopital, Strasbourg 67091, France

[3 ]Department of Medicine, Division of Pulmonary and Critical Care, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA

[4 ]Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA

[5 ]Department of Pathology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA

[6 ]Department of Biomedical Engineering, Department of Electrical and Computer Engineering, and Department of Oncology, Johns Hopkins University, 720 Rutland Avenue, Traylor 710, Baltimore, MD 21205, USA

[7 ] gtearney@ 123456partners.org

[8 ] xingde@ 123456jhu.edu

Article

Accession ID: PMC5480489 Pmcid ID: PMC5480489 Pmc-uid ID: 5480489 Publisher ID: 284474

DOI: 10.1364/BOE.8.002405

PMC ID: 5480489

PubMed ID: 28663882

SO-VID: 85de464a-dab7-4b4e-a24f-522ff2761b6f

History

Date received : 10 January 2017

Date revision received : 20 March 2017

Date accepted : 27 March 2017

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