Mamun Al Mahtab: Role: Data curationRole: InvestigationRole: Methodology
Sheikh Mohammad Fazle Akbar:
ORCID: http://orcid.org/0000-0002-8139-2645
Role: ConceptualizationRole: Formal analysisRole: InvestigationRole: Writing – original
draftRole: Writing – review & editing
Julio Cesar Aguilar: Role: Formal analysisRole: MethodologyRole: Supervision
Gerardo Guillen: Role: ConceptualizationRole: SupervisionRole: Validation
Euduaro Penton: Role: Formal analysisRole: Supervision
Angela Tuero: Role: Formal analysisRole: Software
Osamu Yoshida: Role: Formal analysisRole: Investigation
Yoichi Hiasa: Role: Formal analysisRole: Supervision
Morikazu Onji: Role: Supervision
Vincent Wong: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
22
August
2018
Publication date Collection: 2018
Volume: 13
Issue: 8
Electronic Location Identifier: e0201236
Affiliations
[1
]
Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
[2
]
Department of Medical Sciences, Toshiba General Hospital, Tokyo, Japan
[3
]
Department of Biomedical Research, Center for Genetic Engineering and Biotechnology,
Havana, Cuba
[4
]
Department of Gastroenterology and Metabology, Ehime University Graduate School of
Medicine, Ehime, Japan
[5
]
Department of Medicine, Sai Sei Kai Imabari Hospital, Imabari, Japan
The Chinese University of Hong Kong, HONG KONG
Author notes
Competing Interests: This study was partly funded by the Clinical Research Organization Bangladesh. There
are no patents, products in development or marketed products to declare. This does
not alter our adherence to all the PLOS ONE policies on sharing data and materials,
as detailed online in the guide for authors.
[¤]
Current address: Department of Pathology, Ehime University Proteo-Science Center,
Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime
Author information
Article
Publisher ID:
PONE-D-17-44746
DOI: 10.1371/journal.pone.0201236
PMC ID: 6104936
PubMed ID: 30133478
SO-VID: 861f4686-36aa-487f-9621-529604b6ac61
Copyright © © 2018 Al Mahtab et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
The trial was partially funded by the Center for Genetic Engineering and Biotechnology
(CIGB) (Project name: Hepatitis B Therapeutic Vaccine). CIGB reimbursed Clinical Research
Organization Ltd. (CRO Ltd.) for their efforts. The CIGB provided support in form
of salaries for their authors EP, JCA, GG, and AT. The statistical analysis plan was
written by AT (CIGB). CIGB did not have any additional role in the data collection
and analysis, decision to publish or preparation of the manuscript. The URL of CIGB
is as follows:
http://www.cigb.edu.cu/es/.
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Infectious Diseases
Subject:
Infectious Disease Control
Subject:
Vaccines
Subject:
Research and Analysis Methods
Subject:
Research Design
Subject:
Clinical Research Design
Subject:
Adverse Events
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Vaccination and Immunization
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Vaccination and Immunization
Subject:
Medicine and Health Sciences
Subject:
Public and Occupational Health
Subject:
Preventive Medicine
Subject:
Vaccination and Immunization
Subject:
Medicine and health sciences
Subject:
Clinical medicine
Subject:
Clinical trials
Subject:
Phase III clinical investigation
Subject:
Medicine and health sciences
Subject:
Pharmacology
Subject:
Drug research and development
Subject:
Clinical trials
Subject:
Phase III clinical investigation
Subject:
Research and analysis methods
Subject:
Clinical trials
Subject:
Phase III clinical investigation
Subject:
Medicine and health sciences
Subject:
Infectious diseases
Subject:
Viral diseases
Subject:
Hepatitis
Subject:
Hepatitis B
Subject:
Medicine and health sciences
Subject:
Gastroenterology and hepatology
Subject:
Liver diseases
Subject:
Infectious hepatitis
Subject:
Hepatitis B
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Virology
Subject:
Viral Transmission and Infection
Subject:
Viral Load
Subject:
Medicine and Health Sciences
Subject:
Pharmacology
Subject:
Routes of Administration
Subject:
Medicine and Health Sciences
Subject:
Pharmaceutics
Subject:
Drug Therapy