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      Forensic DNA Typing

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      Annual Review of Criminology
      Annual Reviews

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          Abstract

          Forensic DNA testing has rapidly become an invaluable tool for identifying suspects and proving guilt in criminal cases. But as DNA technologies evolve and databases grow, a broad range of issues concerning the science, statistics, and social policy of forensic DNA testing have surfaced. This article reviews some of the emerging challenges in the field.

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          Most cited references9

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          Convicting the Innocent

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            DNA commission of the International Society of Forensic Genetics: Recommendations on the interpretation of mixtures.

            The DNA commission of the International Society of Forensic Genetics (ISFG) was convened at the 21st congress of the International Society for Forensic Genetics held between 13 and 17 September in the Azores, Portugal. The purpose of the group was to agree on guidelines to encourage best practice that can be universally applied to assist with mixture interpretation. In addition the commission was tasked to provide guidance on low copy number (LCN) reporting. Our discussions have highlighted a significant need for continuing education and research into this area. We have attempted to present a consensus from experts but to be practical we do not claim to have conveyed a clear vision in every respect in this difficult subject. For this reason, we propose to allow a period of time for feedback and reflection by the scientific community. Then the DNA commission will meet again to consider further recommendations.
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              Is Open Access

              Application of Next-generation Sequencing Technology in Forensic Science

              Next-generation sequencing (NGS) technology, with its high-throughput capacity and low cost, has developed rapidly in recent years and become an important analytical tool for many genomics researchers. New opportunities in the research domain of the forensic studies emerge by harnessing the power of NGS technology, which can be applied to simultaneously analyzing multiple loci of forensic interest in different genetic contexts, such as autosomes, mitochondrial and sex chromosomes. Furthermore, NGS technology can also have potential applications in many other aspects of research. These include DNA database construction, ancestry and phenotypic inference, monozygotic twin studies, body fluid and species identification, and forensic animal, plant and microbiological analyses. Here we review the application of NGS technology in the field of forensic science with the aim of providing a reference for future forensics studies and practice.
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                Author and article information

                Journal
                Annual Review of Criminology
                Annu. Rev. Criminol.
                Annual Reviews
                2572-4568
                2572-4568
                January 13 2018
                January 13 2018
                : 1
                : 1
                : 497-515
                Affiliations
                [1 ]School of Law, New York University, New York, NY 10012, USA;
                Article
                10.1146/annurev-criminol-032317-092127
                8623cb9a-c90b-4ae6-be61-4fa74f788c06
                © 2018
                History

                Molecular medicine,Biomedical engineering,Bioinformatics & Computational biology,Biotechnology,Genetics,Public health

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