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      Heat exposure enhances radiosensitivity by depressing DNA-PK kinase activity during double strand break repair.

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          Abstract

          From the role of double strand DNA dependent protein kinase (DNA-PKcs) activity of non-homologous end joining (NHEJ) repair for DNA double strand breaks (DSBs), we aim to define possible associations between thermo-sensitisation and the enzyme activities in X-ray irradiated cells.

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          Author and article information

          Journal
          Int J Hyperthermia
          International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
          1464-5157
          0265-6736
          Mar 2014
          : 30
          : 2
          Affiliations
          [1 ] Department of Radioisotope Medicine, Atomic Bomb Disease and Hibakusha Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University , Nagasaki , Japan .
          Article
          10.3109/02656736.2014.887793
          24571173

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