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      Effect of blueberry feeding on lipids and oxidative stress in the serum, liver and aorta of guinea pigs fed on a high-cholesterol diet.

      Bioscience, biotechnology, and biochemistry
      Animals, Anticholesteremic Agents, pharmacology, Aorta, drug effects, metabolism, pathology, Blueberry Plant, Cholesterol, Dietary, administration & dosage, Diet, High-Fat, Flavonols, Guinea Pigs, Hypercholesterolemia, diet therapy, etiology, Lipid Metabolism, Lipid Peroxidation, Liver, Male, Oxidative Stress, Polyphenols

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          Abstract

          We investigated the effect of blueberries (BB) on lipids and oxidative stress parameters in hypercholesterolemic guinea pigs. The animals were fed for 75 d on a high-cholesterol (HC) diet supplemented with fresh BB. BB reduced oxidative stress and cholesterol accumulation in the aorta and liver of the guinea pigs. This effect may be related to its antioxidative potential and lipid-reducing effect.

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