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Alzheimer Disease: Misfolded diabetes-mellitus peptide seeds amyloid-β aggregation
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Abstract
A misfolded protein present in type 2 diabetes mellitus (T2DM) can exacerbate the aggregation of amyloid-β (Aβ), according to new research.An association has long been recognized between Alzheimer disease (AD) and T2DM. A high risk of dementia is observed in individuals with T2DM, and